Evidence map›Paper›PMID 36997334›Full record

ArticleEuropean heart journal. Quality of care & clinical outcomes2024

Identification of recurrent atrial fibrillation using natural language processing applied to electronic health records.

Chengyi Zheng, Ming-Sum Lee, Nisha Bansal, Alan S Go, Cheng Chen, Teresa N Harrison, Dongjie Fan, Amanda Allen, Elisha Garcia, Ben Lidgard and 2 more

Open access · greenAbstract read
In one paragraph

Article in European heart journal. Quality of care & clinical outcomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Chengyi ZhengResearch and Evaluation Department, Kaiser Permanente Southern California,100 S Los Robles Ave, 2nd Floor, Pasadena, CA 91101, USA.
Ming-Sum LeeDepartment of Cardiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA 90027, USA.
Nisha BansalKidney Research Institute, Division of Nephrology, University of Washington, Seattle, WA 98104, USA.
Alan S GoDivision of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
Cheng ChenDepartment of Cardiology, Kaiser Permanente Fontana Medical Center, Fontana, CA 92335, USA.
Teresa N HarrisonResearch and Evaluation Department, Kaiser Permanente Southern California,100 S Los Robles Ave, 2nd Floor, Pasadena, CA 91101, USA.
Dongjie FanDivision of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
Amanda AllenDivision of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
Elisha GarciaDivision of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
Ben LidgardDepartment of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, CA 91101, USA.
Daniel SingerClinical Epidemiology Unit, Massachusetts General Hospital, Boston, MA 02114, USA.
Jaejin AnResearch and Evaluation Department, Kaiser Permanente Southern California,100 S Los Robles Ave, 2nd Floor, Pasadena, CA 91101, USA.
Kaiser Permanente · USKaiser Permanente Fontana Medical Center · USLos Angeles Medical Center · USMassachusetts General Hospital · USUniversity of Washington · US

Funding

Optimizing Atrial Fibrillation Management in CKDR01HL142834 · NHLBI · UNIVERSITY OF WASHINGTON · PI BANSAL, NISHA, GO, ALAN S · 2019 to 2022
$3.4M
Heart failure and atrial arrhythmias in CKDR01DK103612 · NIDDK · UNIVERSITY OF WASHINGTON · PI BANSAL, NISHA · 2015 to 2018
$1.9M
NHLBI NIH HHS R01 HL142834NIDDK NIH HHS R01 DK103612NIH HHS R01HL142834
6 · The paper itself

Abstract

aimsThis study aimed to develop and apply natural language processing (NLP) algorithms to identify recurrent atrial fibrillation (AF) episodes following rhythm control therapy initiation using electronic health records (EHRs). METHODS AND

resultsWe included adults with new-onset AF who initiated rhythm control therapies (ablation, cardioversion, or antiarrhythmic medication) within two US integrated healthcare delivery systems. A code-based algorithm identified potential AF recurrence using diagnosis and procedure codes. An automated NLP algorithm was developed and validated to capture AF recurrence from electrocardiograms, cardiac monitor reports, and clinical notes. Compared with the reference standard cases confirmed by physicians' adjudication, the F-scores, sensitivity, and specificity were all above 0.90 for the NLP algorithms at both sites. We applied the NLP and code-based algorithms to patients with incident AF (n = 22 970) during the 12 months after initiating rhythm control therapy. Applying the NLP algorithms, the percentages of patients with AF recurrence for sites 1 and 2 were 60.7% and 69.9% (ablation), 64.5% and 73.7% (cardioversion), and 49.6% and 55.5% (antiarrhythmic medication), respectively. In comparison, the percentages of patients with code-identified AF recurrence for sites 1 and 2 were 20.2% and 23.7% for ablation, 25.6% and 28.4% for cardioversion, and 20.0% and 27.5% for antiarrhythmic medication, respectively.

conclusionWhen compared with a code-based approach alone, this study's high-performing automated NLP method identified significantly more patients with recurrent AF. The NLP algorithms could enable efficient evaluation of treatment effectiveness of AF therapies in large populations and help develop tailored interventions.

Indexed as

Atrial FibrillationElectronic Health RecordsAdultAlgorithmsHumansNatural Language ProcessingTreatment OutcomeArtificial intelligenceAtrial fibrillationElectronic health recordNatural language processingRecurrence

Identifiers

PMID36997334
PMCPMC10785579
OpenAlexW4361236004

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.