SynthesisPloS one2023
Association between hypoalbuminemia and mortality in patients undergoing continuous renal replacement therapy: A systematic review and meta-analysis.
Synthesis in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 13 citations in OpenAlex.
- Anaemia, hypoalbuminemia, and risk of cycloserine-associated neuropsychiatric toxicity in a shortened oral regimen for multidrug/rifampicin-resistant TB.IJTLD open · 2026Article
- Article
- Risk factors, resistance profiles, and clinical outcomes ofFrontiers in cellular and infection microbiology · 2026Article
- Nutritional-inflammatory-metabolic indices associated with in-hospital mortality in acute kidney injury patients undergoing continuous renal replacement therapy: dose-response analysis and machine learning-based risk stratification.Frontiers in nutrition · 2026Article
- Article
- Mediation effects of age, intramuscular adipose tissue index and serum albumin on survival status in initial dialysis patients.Renal failure · 2025Article
- Age-stratified mortality and associated risk factors in adults aged 65 years or older undergoing continuous kidney replacement therapy: a consecutive retrospective study.BMC nephrology · 2025Article
- A study on the factors influencing mortality risk in sepsis-induced acute kidney injury based on analysis of the MIMIC database.Clinical and experimental medicine · 2025Article
- Association of Albumin-to-D-Dimer Ratio with Mortality in Mechanically Ventilated Intensive Care Patients.Journal of clinical medicine · 2025Article
- Serum creatinine-to-albumin ratio predicts mortality in hemorrhagic stroke: a novel threshold for risk stratification.Neurosurgical review · 2025Article
- The Impact of Hypoalbuminemia on Inflammatory Markers, Serum Creatinine, Hemoglobin and Outcome in Critically ill Patients With COVID-19 Infection-Retrospective Observation Study.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2025Article
- Microbiota-friendly diet ameliorates hypoalbuminemia in chronic kidney disease: evidence from NHANES.Frontiers in immunology · 2025Article
- Continuous Renal Replacement Therapy: Application of Kidney Disease Improving Global Outcomes Guidelines for Treatment Prescription in Dogs With Acute Kidney Injury and Outcome Prediction.Journal of veterinary internal medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The review aimed to assess if hypoalbuminemia can predict mortality in patients undergoing continuous renal replacement therapy (CRRT). PubMed, Web of Science, Embase, and CENTRAL were searched for relevant articles published up to 24 July 2022. Adjusted data were pooled to calculate the odds ratio (OR). Sensitivity and meta-regression analysis was conducted. Five studies with 5254 patients were included. Meta-analysis of all five studies demonstrated that hypoalbuminemia was a significant predictor of mortality after CRRT (OR: 1.31 95% CI: 1.07, 1.60 I2 = 72% p = 0.01). The results did not change on sensitivity analysis. On meta-regression, we noted that variables like age, male gender, BMI, percentage of diabetics, and pre-CRRT SOFA score had no statistically significant influence on the outcome. Data from a limited number of studies suggest that hypoalbuminemia before initiation of CRRT is an independent predictor of early mortality. Based on current evidence, it may be suggested that patients with low albumin levels initiating CRRT should be prioritized and treated aggressively to reduce adverse outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.