Evidence map›Paper›PMID 36995951›Full record

ArticleeLife2023

Human thymopoiesis produces polyspecific CD8

Valentin Quiniou, Pierre Barennes, Vanessa Mhanna, Paul Stys, Helene Vantomme, Zhicheng Zhou, Federica Martina, Nicolas Coatnoan, Michele Barbie, Hang-Phuong Pham and 8 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Review
  6. Review
  7. AnalyzAIRR: A user-friendly guided workflow for AIRR data analysis.Immunoinformatics (Amsterdam, Netherlands) · 2025
    Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 2 countries.

Valentin QuiniouSorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy, Paris, France.ORCID 0000-0002-0792-341X
Pierre Barennes *Sorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy, Paris, France.
Vanessa Mhanna *Sorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy, Paris, France.ORCID 0000-0002-9354-7210
Paul Stys *Sorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy, Paris, France.
Helene Vantomme *Sorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy, Paris, France.
Zhicheng Zhou *Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France.ORCID 0000-0001-9137-7951
Federica MartinaAP-HP, Hôpital Pitié-Salpêtrière, Clinical Investigation Center for Biotherapies (CIC-BTi) and Immunology-Inflammation-Infectiology and Dermatology Department (3iD), Paris, France.
Nicolas CoatnoanAP-HP, Hôpital Pitié-Salpêtrière, Clinical Investigation Center for Biotherapies (CIC-BTi) and Immunology-Inflammation-Infectiology and Dermatology Department (3iD), Paris, France.
Michele BarbieAP-HP, Hôpital Pitié-Salpêtrière, Clinical Investigation Center for Biotherapies (CIC-BTi) and Immunology-Inflammation-Infectiology and Dermatology Department (3iD), Paris, France.
Hang-Phuong PhamILTOO pharma, Statistical department, Paris, France.
Béatrice ClémenceauCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Henri VieCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Mikhail ShugayCenter of Life Sciences, Skoltech, Moscow, Russian Federation.ORCID 0000-0001-7826-7942
Adrien SixSorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy, Paris, France.
Barbara BrandaoUniversité Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France.
Roberto MalloneUniversité Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France.
Encarnita Mariotti-FerrandizSorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy, Paris, France.
David KlatzmannSorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy, Paris, France.ORCID 0000-0002-0054-3422
Inserm · FRCentre National de la Recherche Scientifique · FRSkolkovo Institute of Science and Technology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T-cell receptors (TCRs) are formed by stochastic gene rearrangements, theoretically generating >10

Indexed as

Antigens, ViralCD8-Positive T-LymphocytesHumansPeptidesReceptors, Antigen, T-CellReceptors, Antigen, T-Cell, alpha-betaAntigens, ViralPeptidesReceptors, Antigen, T-CellReceptors, Antigen, T-Cell, alpha-betaautoimmunitycross-reactivityheterologous immunityhumanimmunologyimmunopathologyinflammationmousepolyspecificityTCRThymopoiesis

Identifiers

PMID36995951
PMCPMC10063231
OpenAlexW4361269674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.