Evidence map›Paper›PMID 36995910›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2023

STIM1 ablation impairs exercise-induced physiological cardiac hypertrophy and dysregulates autophagy in mouse hearts.

Ingrid M Bonilla, Stephen Baine, Anastasia Pokrass, Juan Ignacio Elio Mariángelo, Anuradha Kalyanasundaram, Vladimir Bogdanov, Louisa Mezache, Galina Sakuta, Casey M Beard, Andriy Belevych and 7 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Molecular mechanism on autophagy associated cardiovascular dysfunction inFrontiers in cell and developmental biology · 2025
    Review
  2. Article
  3. Review
  4. Review
  5. Role of STIM1 in the Regulation of Cardiac Energy Substrate Preference.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 2 countries.

Ingrid M BonillaDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.ORCID 0000-0003-1435-3870
Stephen BaineDepartment of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States.
Anastasia PokrassDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
Juan Ignacio Elio MariángeloDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
Anuradha KalyanasundaramDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
Vladimir BogdanovDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
Louisa MezacheDepartment of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, Ohio, United States.
Galina SakutaDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
Casey M BeardDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
Andriy BelevychDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
Svetlana TikunovaDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.ORCID 0000-0002-2101-9996
Radmila TerentyevaDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
Dmitry TerentyevDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.ORCID 0000-0002-9530-7384
Jonathan DavisDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
Rengasayee VeeraraghavanDepartment of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, Ohio, United States.
Cynthia A CarnesDepartment of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States.
Sandor GyörkeDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States.ORCID 0000-0002-0821-1983
The Ohio State University · USUniversity of Puerto Rico System · PR

Funding

CONTROLLED AND UNCONTROLLABLE CALCIUM RELEASE IN HEARTR01HL063043 · NHLBI · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI Sandor Gyorke · 1999 to 2026
$8.6M
Ryanodine Receptor Channels in Heart FailureR01HL074045 · NHLBI · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI GYORKE, SANDOR · 2003 to 2024
$8.2M
Novel Mechanisms of Regulation of SK channels: Implications for Cardiac ArrhythmiaR01HL142588 · NHLBI · OHIO STATE UNIVERSITY · PI TERENTYEV, DMITRY A · 2019 to 2022
$2.4M
NHLBI NIH HHS R01 HL063043NHLBI NIH HHS R01 HL074045NHLBI NIH HHS R01 HL142588
6 · The paper itself

Abstract

Cardiac stromal interaction molecule 1 (STIM1), a key mediator of store-operated Ca

Indexed as

Calcium ChannelsMyocytes, CardiacAnimalsCalciumCalcium SignalingCardiomegalyMammalsMiceMice, KnockoutProto-Oncogene Proteins c-aktStromal Interaction Molecule 1TOR Serine-Threonine KinasesCalciumCalcium ChannelsProto-Oncogene Proteins c-aktStim1 protein, mouseStromal Interaction Molecule 1TOR Serine-Threonine Kinasescalciumcardiac hypertrophyexerciseSOCESTIM1

Identifiers

PMID36995910
PMCPMC10190841
OpenAlexW4361269635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.