Evidence map›Paper›PMID 36995818›Full record

Trial reportActa cirurgica brasileira2023

Minimal and normal-flow general anesthesia in patients undergoing surgery in prone position: ımpact on hemodynamics and regional cerebral oxygenation.

Esra Akdaş Tekin, Fethi Gültop, Nihan Altıntepe Başkurt

Registry-linked trialOpen access · greenFull text readRandomized Controlled Trial
In one paragraph

Trial report in Acta cirurgica brasileira, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06896604 (Comparison of the Effects of Low-Flow and High-Flow Desflurane Anesthesia on Optic Nerve Sheath Diameter in Laparoscopic Cholecystectomy Surgeries), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06896604 completednot on this mapstarted 2025, after this paper: background citation

Comparison of the Effects of Low-Flow and High-Flow Desflurane Anesthesia on Optic Nerve Sheath Diameter in Laparoscopic Cholecystectomy Surgeries

TypeobservationalSponsorFatih Sultan Mehmet Training and Research HospitalRan2025 to 2025Enrolled64ConditionsOptic Nerve Sheath DiameterArmsOcular Ultrasonography for measuring Optic Nerve Sheath Diameter
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. A Comparative Study on Minimal Flow Anaesthesia in Geriatric and Middle-aged Patients.Turkish journal of anaesthesiology and reanimation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Esra Akdaş TekinUniversity of Health Sciences Prof. Dr. Cemil Tascioglu City Hospital - Department of Anestesiology and Reanimation - Istanbul, Turkey.ORCID http://orcid.org/0000-0001-8538-2893
Fethi GültopUniversity of Health Sciences Prof. Dr. Cemil Tascioglu City Hospital - Department of Anestesiology and Reanimation - Istanbul, Turkey.ORCID http://orcid.org/0000-0002-1206-2765
Nihan Altıntepe BaşkurtUniversity of Health Sciences Prof. Dr. Cemil Tascioglu City Hospital - Department of Anestesiology and Reanimation - Istanbul, Turkey.ORCID http://orcid.org/0000-0001-6868-948X
Sağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this study, the aim to assess the combined effects of prone-positioning (PP) and minimal-flow (MF) general anesthesia on regional cerebral oxygenation (RCO) and systemic hemodynamics.

methodsThis is a randomized prospective study aiming to evaluate changes in cerebral oxygenation and hemodynamic parameters in MF systemic anesthesia in patients undergoing surgery in PP. Patients were randomized to MF or normal-flow (NF) anesthesia. In the operating room, pulse rate, mean arterial pressure (MAP), peripheral hemoglobin oxygen saturation (spO2), and right- and left-side RCO (assessed by near-infrared spectroscopy, NIRS) were measured perioperatively.

resultsOverall, 46 patients were included (24 in the MF group and 22 in the NF group). The amount of anesthetic gas consumption was significantly lower in the low-flow (LF) group. In both groups, the mean pulse rate showed a decrease after PP. Before induction, RCO was significantly higher both at the right- and left-sides in the LF group compared to the NF group. This difference continued throughout the operation on the left-side and disappeared 10 min after intubation on the right-side. On the left side, mean RCO decreased after PP in both groups.

conclusionsMF anesthesia in PP did not reduce cerebral oxygenation compared to NF and was safe in terms of systemic hemodynamics and cerebral oxygenation.

Indexed as

Anesthesia, GeneralPatient PositioningHemodynamicsHumansOxygenProne PositionProspective StudiesOxygen

Identifiers

PMID36995818
PMCPMC10042492
OpenAlexW4361303067

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read36
identifiers read1
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.