Evidence map›Paper›PMID 36995692›Full record

SynthesisEuropean journal of orthodontics2023

Malocclusions and quality of life among adolescents: a systematic review and meta-analysis.

Emma Göranson, Mikael Sonesson, Aron Naimi-Akbar, Lillemor Dimberg

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European journal of orthodontics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 37 citations in OpenAlex.

  1. Trial
  2. Letter to editor regarding "Influence of general orthodontic treatment need and of specific anterior malocclusions on oral health-related quality of life in children and adolescents with class II malocclusion".Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026
    Article
  3. Article
  4. Influence of upper anterior teeth crowding on the quality of life of children and adolescents.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026
    Article
  5. Article
  6. Positive Longitudinal Caregiver Behavioral Ratings and Self-Reported Quality of Life in Youth With Cleft Lip and Palate in Treatment for Class III Malocclusion.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  7. Observational
  8. Article
  9. Article
  10. Effects of malocclusion and orthodontic treatment on quality of life among orthodontic patients with craniofacial disorder compared to healthy controls : A cross-sectional study.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Impact of pulp involvement due to caries on oral health-related quality of life in Brazilian schoolchildren: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Emma GöransonCenter for Orthodontics and Pediatric Dentistry, Norrköping, Public Dental Service Östergötland, Norrköping, Sweden.
Mikael SonessonDepartment of Orthodontics, Malmö University, Malmö, Sweden.ORCID 0000-0001-8422-9344
Aron Naimi-AkbarHTA-O Health Technology in Odontology, Malmö University, Malmö, Sweden.
Lillemor DimbergDepartment of Orthodontics, Malmö University, Malmö, Sweden.
Malmö University · SELinköping University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalocclusions in adolescents might have a negative impact on oral health-related quality of life (OHRQoL). Potential confounding variables (confounders) such as age, gender, caries, and socioeconomic status may skew the real relationship between malocclusions and OHRQoL.

objectivesTo analyse the effect of malocclusions in adolescents on OHRQoL, when controlled for potential confounders. SEARCH

methodsFive databases (PubMed, Cochrane Library, Cinahl, Scopus, and Web of Science) were searched up to 15 June 2022. SELECTION CRITERIA: Studies in which OHRQoL in 10-19-year olds with and without malocclusions were compared. DATA COLLECTION AND ANALYSIS: Screening, data extraction, and quality assessments were performed by four investigators independently. Risk of bias was assessed according to the Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) guidelines. To be included, studies had to control for confounders. Certainty of evidence was assessed with GRADE.

resultsThirteen cross-sectional studies with low and moderate risk of bias were included in the qualitative synthesis. Four of these were also included in the quantitative synthesis (meta-analysis). The 13 studies in the qualitative synthesis displayed a large variation among the indices used for malocclusion ratings, as well as in instruments measuring OHRQoL. There was moderate quality of evidence that malocclusions have a negative effect on OHRQoL. The four articles included in the quantitative synthesis (meta-analysis) measured malocclusions with DAI and OHRQoL with CPQ 11-14 short form. There was moderate quality of evidence that malocclusions have a negative effect on OHRQoL (RR/PR 1.15, 95% CI 1.12-1.18, 3672 participants).

conclusionsThere is moderate quality of evidence that malocclusions in adolescents have a negative impact on OHRQoL, after taking relevant confounders into consideration. Future studies should ideally use standardized measures for malocclusion ratings and OHRQoL. REGISTRATION: PROSPERO. CRD42020186152.

Indexed as

Dental CariesMalocclusionAdolescentCross-Sectional StudiesHumansOral HealthQuality of Life

Identifiers

PMID36995692
PMCPMC10230246
OpenAlexW4361263043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.