ArticleDermatology and therapy2023
Self-Esteem, Depression, Anxiety and Quality of Life in Patients with Melasma Living in a Sunny Mediterranean Area: Results from a Prospective Cross-Sectional Study.
Article in Dermatology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Prevalence of depression in melasma: a systematic review and meta-analysis.Frontiers in psychiatry · 2023Pooled it
- Microneedling-assisted delivery of metformin versus tranexamic acid in treating melasma: a randomized controlled study.European journal of medical research · 2025Trial
- Combination Approach to Hyperpigmentation: Unveiling Enhanced Aesthetic Results With Microneedling and Pigment-Correcting Peel.The Journal of clinical and aesthetic dermatology · 2026Article
- A Retrospective Analysis of Radiofrequency Microneedling for Melasma Management in the Japanese Population.Clinical, cosmetic and investigational dermatology · 2026Article
- Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology.Journal of cosmetic dermatology · 2026Review
- Knowledge, attitudes, and practices regarding melasma among female patients.Frontiers in public health · 2026Article
- Efficacy and Tolerability of a New Facial 2-Mercaptonicotinoyl Glycine-Containing Depigmenting Serum Versus Hydroquinone 4% over 3-Month Treatment of Facial Melasma.Dermatology and therapy · 2025Article
- Prevalence and associated factors of depression and anxiety among patients with melasma: a cross-sectional study in China.Frontiers in psychiatry · 2025Article
- Valorization of Hom Thong Banana Peel (International journal of molecular sciences · 2024Article
- Melasma: A Clinical and Epidemiological Single-Group Observational Study in the Greek Population.Dermatology and therapy · 2024Article
- The aggressive face of melasma: unveiling the influence of upper lip pigmentation on social perception.Postepy dermatologii i alergologii · 2024Article
- Melasma: A Step-by-Step Approach Towards a Multimodal Combination Therapy.Clinical, cosmetic and investigational dermatology · 2024Review
- Depressive and anxious symptoms in melasma during pregnancy: a cross-sectional study.Anais brasileiros de dermatologiaArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMelasma is a common acquired disorder of hyperpigmentation and has a significant effect on quality of life. The aim of this prospective cross-sectional study was to assess the effect of melasma on depression, social anxiety and self-esteem in the Greek population.
methodsThe study included a total of 254 participants: 127 patients with melasma and an equal sample of healthy controls. Both participant groups completed the following psychometric measures: the Hospital Anxiety and Depression Scale (HADS) to assess anxiety and depression and Rosenberg's Self-esteem Scale (RSES) for self-esteem. Furthermore, in patients with melasma, quality of life was assessed using Melasma Quality of Life (MELASQoL).
resultsMelasma patients (7.47 ± 4.53) presented statistically significantly higher anxiety compared to healthy controls (6.06 ± 3.59, p = 0.006), while no differences emerged with regard to depression or self-esteem. It is important to note that the difference regarding anxiety remained significant (b = 1.25, p = 0.003) even after adjusting for age, depression and self-esteem. A higher disease severity (MASI) correlated statistically significantly with longer disease duration (r = 0.24, p < 0.001), higher depression (r = 0.28, p = 0.002), and a more impaired health-related quality of life (MelasQol; r = 0.29, p < 0.001). Notably, a more impaired health-related quality of life was also correlated with higher depression (r = 0.19, p = 0.027) and lower self-esteem (r = - 0.31, p < 0.001).
conclusionThe results of this study highlight the importance of evaluating quality of life, anxiety and depression in patients with melasma. The therapeutic approach should not be based solely on clinical findings; it should also include an evaluation of the patient's psychological aspects. Dermatologists can further improve their patient care by being supportive or requesting psychological intervention when needed, resulting in better compliance with treatment and an improved social and psychological status.
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