Evidence map›Paper›PMID 36995467›Full record

ArticleInsights into imaging2023

Integrative diagnostics: the time is now-a report from the International Society for Strategic Studies in Radiology.

Norman J Beauchamp, R Nick Bryan, Marilyn M Bui, Gabriel P Krestin, Geraldine B McGinty, Carolyn C Meltzer, Michael Neumaier

Abstract read
In one paragraph

Article in Insights into imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  3. Strategy of Laboratory Medicine - EFLM Vision.Clinical chemistry and laboratory medicine · 2026
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Norman J BeauchampMichigan State University, East Lansing, MI, USA.
R Nick BryanUniversity of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA. robert.bryan@pennmedicine.upenn.edu.
Marilyn M BuiMoffitt Cancer Center and Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Gabriel P KrestinErasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Geraldine B McGintyWeill Cornell Medicine, New York, NY, USA.
Carolyn C MeltzerKeck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Michael NeumaierMedical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enormous recent progress in diagnostic testing can enable more accurate diagnosis and improved clinical outcomes. Yet these tests are increasingly challenging and frustrating; the volume and diversity of results may overwhelm the diagnostic acumen of even the most dedicated and experienced clinician. Because they are gathered and processed within the "silo" of each diagnostic discipline, diagnostic data are fragmented, and the electronic health record does little to synthesize new and existing data into usable information. Therefore, despite great promise, diagnoses may still be incorrect, delayed, or never made. Integrative diagnostics represents a vision for the future, wherein diagnostic data, together with clinical data from the electronic health record, are aggregated and contextualized by informatics tools to direct clinical action. Integrative diagnostics has the potential to identify correct therapies more quickly, modify treatment when appropriate, and terminate treatment when not effective, ultimately decreasing morbidity, improving outcomes, and avoiding unnecessary costs. Radiology, laboratory medicine, and pathology already play major roles in medical diagnostics. Our specialties can increase the value of our examinations by taking a holistic approach to their selection, interpretation, and application to the patient's care pathway. We have the means and rationale to incorporate integrative diagnostics into our specialties and guide its implementation in clinical practice.

Indexed as

DiagnosticsInformaticsPathologyRadiology

Identifiers

PMID36995467
PMCPMC10063732

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.