Evidence map›Paper›PMID 36995319›Full record

ArticleThe Journal of general physiology2023

About hysteresis in Shaker: Response to note by Villalba-Galea.

Baron Chanda, John Cowgill

Open access · bronzeAbstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of general physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Baron ChandaDepartments of Anesthesiology, Neuroscience, Biochemistry and Molecular Biophysics, Center for Investigation of Membrane Excitability Diseases, Washington University School of Medicine , St. Louis, MO, USA.ORCID 0000-0003-4954-7034
John CowgillDepartments of Anesthesiology, Neuroscience, Biochemistry and Molecular Biophysics, Center for Investigation of Membrane Excitability Diseases, Washington University School of Medicine , St. Louis, MO, USA.
Washington University in St. Louis · US

Funding

Biophysical mechanisms of gating and modulation in voltage-gated ion channel superfamilyR35NS116850 · NINDS · WASHINGTON UNIVERSITY · PI Baron Chanda · 2020 to 2026
$6.9M
Thermodynamics and Energetics of voltage-gated ion channelsR01NS081293 · NINDS · WASHINGTON UNIVERSITY · PI CHANDA, BARON · 2012 to 2019
$2.9M
NINDS NIH HHS R01 NS081293NINDS NIH HHS R35 NS116850
6 · The paper itself

Abstract

In this issue, Villalba-Galea (2023. J. Gen. Physiol.https://doi.org/10.1085/jgp.202313371) expresses interest in our recently published work (Cowgill and Chanda. 2023. J. Gen. Physiol.https://doi.org/10.1085/jgp.202112883). Our response points out the deficiencies in the alternative explanation proposed by Villalba-Galea to account for our findings on hysteresis (or lack thereof) in steady state charge-voltage curves of Shaker potassium channel.

Indexed as

Potassium ChannelsPotassium Channels

Identifiers

PMID36995319
PMCPMC10067699
OpenAlexW4361305476

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.