Evidence map›Paper›PMID 36995240›Full record

ArticleMicrobiology spectrum2023

Protein Disulfide Isomerase and Extracellular Adherence Protein Cooperatively Potentiate Staphylococcal Invasion into Endothelial Cells.

Marleen Leidecker, Anne Bertling, Muzaffar Hussain, Markus Bischoff, Johannes A Eble, Anke C Fender, Kerstin Jurk, Christine Rumpf, Mathias Herrmann, Beate E Kehrel and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Marleen Leidecker *Institute of Medical Microbiology, University Hospital of Münster, Münster, Germany.
Anne Bertling *Department of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostasis, University Hospital of Münster, Münster, Germany.
Muzaffar HussainInstitute of Medical Microbiology, University Hospital of Münster, Münster, Germany.
Markus BischoffInstitute of Medical Microbiology and Hygiene, Saarland University, Homburg, Germany.
Johannes A EbleInstitute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany.
Anke C FenderDepartment of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostasis, University Hospital of Münster, Münster, Germany.
Kerstin JurkDepartment of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostasis, University Hospital of Münster, Münster, Germany.
Christine RumpfInstitute of Medical Microbiology, University Hospital of Münster, Münster, Germany.
Mathias HerrmannInstitute of Medical Microbiology, University Hospital of Münster, Münster, Germany.
Beate E KehrelDepartment of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostasis, University Hospital of Münster, Münster, Germany.
Silke NiemannInstitute of Medical Microbiology, University Hospital of Münster, Münster, Germany.ORCID 0000-0002-9807-2541
University Hospital Münster · DEInstitute of Medical Microbiology and Hygiene · DEJohannes Gutenberg University Mainz · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasion of host cells is an important feature of Staphylococcus aureus. The main internalization pathway involves binding of the bacteria to host cells, e.g., endothelial cells, via a fibronectin (Fn) bridge between S. aureus Fn binding proteins and α

Indexed as

Adhesins, BacterialStaphylococcal InfectionsBacterial ProteinsEndothelial CellsHumansIntegrinsProtein Disulfide-IsomerasesStaphylococcusStaphylococcus aureusAdhesins, BacterialBacterial ProteinsIntegrinsProtein Disulfide-Isomerasesextracellular adherence proteinprotein disulfide isomeraseStaphylococcus aureus host cell invasion

Identifiers

PMID36995240
PMCPMC10269700
OpenAlexW4361270404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.