ArticlePediatrics2023
Maternal and Newborn Hospital Outcomes of Perinatal SARS-CoV-2 Infection: A National Registry.
Article in Pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- The Overlap of Maternal and Neonatal Critical Care Admission in the United States: Trends and Risk Factors in 2016-2024.Journal of clinical medicine · 2026Article
- COVID-19 and Global Perinatal Health: Lessons Learned on Maternal-Neonatal Outcomes, Infant Feeding Practices, and Health Care Economics across Income Settings.American journal of perinatology · 2026Article
- Impact of COVID-19 respiratory conditions on pregnancy outcomes in California.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Safety and efficacy of COVID-19 vaccines in pregnant and lactating women: a comprehensive review.Inflammopharmacology · 2026Review
- Health Care-Associated Infections Among Neonates During the COVID-19 Pandemic.JAMA network open · 2026Article
- Severe acute respiratory syndrome coronavirus 2 and preterm birth, clinical implications-A register-based cohort study from Sweden.Pregnancy (Hoboken, N.J.) · 2025Article
- Inequalities in Preterm Birth in England: A Retrospective National Cohort Study Focusing on Deprivation and Ethnicity, Using Routinely Collected Maternity Hospital Data.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Article
- Neonatal Feeding Practices and SARS-CoV-2 Transmission in Neonates with Perinatal SARS-CoV-2 Exposure: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Impact of COVID-19 in pregnancy on maternal and perinatal outcomes during the Delta variant period: a comparison of the Delta and pre-delta time periods, 2020-2021.Maternal health, neonatology and perinatology · 2024Article
- Serological Outcome in the First Months of Life of Children Born to Mothers with SARS-CoV-2 Infection during Pregnancy.Children (Basel, Switzerland) · 2024Article
- Article
- Characteristics and outcomes of neonates hospitalised with SARS-CoV-2 infection in the UK by variant: a prospective national cohort study.Archives of disease in childhood. Fetal and neonatal edition · 2024Article
- Prenatal Infection by Respiratory Viruses Is Associated with Immunoinflammatory Responses in the Fetus.American journal of respiratory and critical care medicine · 2024Article
- Impacts of maternal COVID-19 during pregnancy on neonatal health and epidemiology.Clinical and experimental pediatrics · 2024Article
- Global prevalence of infections in newborns with respiratory complications: systematic review and meta-analysis.Iranian journal of microbiology · 2024Article
- Adverse perinatal outcomes in gestational diabetes mellitus with and without SARS-CoV-2 infection during pregnancy: results from two nationwide registries in Germany.BMJ open diabetes research & care · 2024Observational
- Trends in COVID-19 diagnoses and outcomes in infants hospitalized in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- COVID-19 among infants: key clinical features and remaining controversies.Clinical and experimental pediatrics · 2024Article
- Neonatal outcomes of maternal prenatal coronavirus infection.Pediatric research · 2024Review
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
objectivesThe American Academy of Pediatrics National Registry for the Surveillance and Epidemiology of Perinatal coronavirus disease 2019 (COVID-19) (NPC-19) was developed to provide information on the effects of perinatal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
methodsNational Registry for the Surveillance and Epidemiology of Perinatal COVID-19 participating centers entered maternal and newborn data for pregnant persons who tested positive for SARS-CoV-2 infection between 14 days before and 10 days after delivery. Incidence of and morbidities associated with maternal and newborn SARS-CoV-2 infection were assessed.
resultsFrom April 6, 2020 to March 19, 2021, 242 centers in the United States centers reported data for 7524 pregnant persons; at the time of delivery, 78.1% of these persons were asymptomatic, 18.2% were symptomatic but not hospitalized specifically for COVID-19, 3.4% were hospitalized for COVID-19 treatment, and 18 (0.2%) died in the hospital of COVID-related complications. Among 7648 newborns, 6486 (84.8%) were tested for SARS-CoV-2, and 144 (2.2%) were positive; the highest rate of newborn infection was observed when mothers first tested positive in the immediate postpartum period (17 of 125, 13.6%). No newborn deaths were attributable to SARS-CoV-2 infection. Overall, 15.6% of newborns were preterm: among tested newborns, 30.1% of polymerase chain reaction-positive and 16.2% of polymerase chain reaction-negative were born preterm (P < .001). Need for mechanical ventilation did not differ by newborn SARS-CoV-2 test result, but those with positive tests were more likely to be admitted to a NICU.
conclusionsEarly in the pandemic, SARS-CoV-2 infection was acquired by newborns at variable rates and without apparent short-term effects. During a period that preceded widespread availability of vaccines, we observed higher than expected numbers of preterm births and maternal in-hospital deaths.
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