Evidence map›Paper›PMID 36994283›Full record

ArticleCureus2023

Acute Sepsis-Induced Cholestatic Disease Presenting With Isolated Hyper-Bilirubinemia.

Nariman Hossein-Javaheri, Omar Rafa, Alyssa Reese, Amera Alsalahi

Open access · diamondFull text readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nariman Hossein-JavaheriInternal Medicine, University at Buffalo, Buffalo, USA.
Omar RafaInternal Medicine, University at Buffalo, Buffalo, USA.
Alyssa ReeseOtolaryngology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, USA.
Amera AlsalahiInternal Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, USA.
University at Buffalo, State University of New York · USJacobs Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis-induced cholestatic disease occurs in a fair amount of critically-ill patients. Although the mechanism is poorly understood, hypoperfusion to the liver is one of the most common mechanisms that lead to liver dysfunction and subsequently biliary disease. Hepatic conditions such as cirrhosis and hepatitis A may have an impact on how sepsis-induced cholestatic disease can present. Understanding the presentation of sepsis-induced cholestasis and addressing the underlying cause of sepsis can certainly lead to better outcomes without the need for procedure intervention. We explore a patient with acute sepsis-induced cholestatic disease who had recently-resolving hepatitis A infection and underlying cirrhosis.

Indexed as

cholestatic liver diseasecirrhosisgastroenterologyhepatitis-asevere sepsis

Identifiers

PMID36994283
PMCPMC10042527
OpenAlexW4321604726

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read12
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.