Evidence map›Paper›PMID 36994233›Full record

ReviewJAC-antimicrobial resistance2023

Mitigating antimicrobial resistance (AMR) using implementation research: a development funder's approach.

Mark P Khurana, Sabiha Essack, Ghada Zoubiane, Nandini Sreenivasan, Gloria Cristina Cordoba, Erica Westwood, Anders Dalsgaard, Robinson H Mdegela, Mirfin Mpundu, Rodrigo Scotini and 22 more

Full text readReview
In one paragraph

Review in JAC-antimicrobial resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Microbiology (Reading, England) · 2025
    Review
  8. Article
  9. Article
  10. Antimicrobial resistance profiles ofJAC-antimicrobial resistance · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Mark P KhuranaICARS, International Centre for Antimicrobial Resistance Solutions, Ørestads Boulevard 5, Copenhagen 2300, Denmark.ORCID https://orcid.org/0000-0002-1123-7674
Sabiha EssackICARS, International Centre for Antimicrobial Resistance Solutions, Ørestads Boulevard 5, Copenhagen 2300, Denmark.ORCID https://orcid.org/0000-0003-3357-2761
Ghada ZoubianeICARS, International Centre for Antimicrobial Resistance Solutions, Ørestads Boulevard 5, Copenhagen 2300, Denmark.
Nandini SreenivasanICARS, International Centre for Antimicrobial Resistance Solutions, Ørestads Boulevard 5, Copenhagen 2300, Denmark.
Gloria Cristina CordobaICARS, International Centre for Antimicrobial Resistance Solutions, Ørestads Boulevard 5, Copenhagen 2300, Denmark.
Erica WestwoodICARS, International Centre for Antimicrobial Resistance Solutions, Ørestads Boulevard 5, Copenhagen 2300, Denmark.
Anders DalsgaardICARS, International Centre for Antimicrobial Resistance Solutions, Ørestads Boulevard 5, Copenhagen 2300, Denmark.
Robinson H MdegelaDepartment of Veterinary Medicine and Public Health, Sokoine University of Agriculture, Morogoro, Tanzania.
Mirfin MpunduICARS, International Centre for Antimicrobial Resistance Solutions, Ørestads Boulevard 5, Copenhagen 2300, Denmark.
Rodrigo ScotiniWorld Diabetes Foundation, Bagsværd 2880, Denmark.
Augustine B MatondoDepartment of Veterinary Medicine and Public Health, Sokoine University of Agriculture, Morogoro, Tanzania.
Alexanda MzulaDepartment of Veterinary Medicine and Public Health, Sokoine University of Agriculture, Morogoro, Tanzania.
Nina ChanishviliGeorge Eliava Institute of Bacteriophage Microbiology and Virology, Gotua Street 3, Tbilisi 0160, Georgia.
Dimitri GogebashviliLTD Invet Group, 84a, Vakhushti Bagrationi Street, Tbilisi 0154, Georgia.
Maia BeruashviliMinistry of Environmental Protection and Agriculture of Georgia, Marshal Gelovani 6, Tbilisi 0159, Georgia.
Marika TsereteliDepartment of Communicable Diseases, National Center for Disease Control and Public Health, Kakheti Highway 99, Tbilisi 0198, Georgia.
Talant SooronbaevNational Center of Cardiology and Internal Medicine named after academician M. Mirrakhimov, Togolok Moldo Str, 3, Bishkek 720040, Kyrgyzstan.
Jesper KjærgaardDepartment of Children and Adolescents, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark.
Joakim BlochDepartment of Children and Adolescents, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark.
Elvira IsaevaNational Center of Maternity and Childhood Care, Akhunbaev Str, 190, Bishkek 720038, Kyrgyzstan.
Geoffrey MaindaDepartment of Veterinary Services, Ministry of Fisheries and Livestock, PO Box 50060, Lusaka, Zambia.
Geoffrey MuukaDepartment of Veterinary Services, Ministry of Fisheries and Livestock, PO Box 50060, Lusaka, Zambia.
Ntombi B MudendaSchool of Veterinary Medicine, University of Zambia, PO Box 32379, Lusaka, Zambia.
Fusya Y GomaDepartment of Veterinary Services, Ministry of Fisheries and Livestock, PO Box 50060, Lusaka, Zambia.
Duc-Huy ChuDepartment of Animal Health, Ministry of Agriculture and Rural Development, Ha Noi 115-19, Viet Nam.
Duncan ChandaUniversity Teaching Hospital, Box 17, UTH Post Office, Nationalist Rd., Lusaka, Zambia.ORCID https://orcid.org/0000-0001-5477-9054
Uchizi ChirwaUniversity Teaching Hospital, Box 17, UTH Post Office, Nationalist Rd., Lusaka, Zambia.
Kaunda YambaSchool of Veterinary Medicine, University of Zambia, PO Box 32379, Lusaka, Zambia.
Kenneth KapoloweUniversity Teaching Hospital, Box 17, UTH Post Office, Nationalist Rd., Lusaka, Zambia.
Sombo FwoloshiUniversity Teaching Hospital, Box 17, UTH Post Office, Nationalist Rd., Lusaka, Zambia.
Lawrence MwengeZambart, Health Economics Unit, Ridgeway, Zambia.
Robert SkovICARS, International Centre for Antimicrobial Resistance Solutions, Ørestads Boulevard 5, Copenhagen 2300, Denmark.ORCID https://orcid.org/0000-0002-6079-5381

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the escalating burden of antimicrobial resistance (AMR), the global response has not sufficiently matched the scale and scope of the issue, especially in low- and middle-income countries (LMICs). While many countries have adopted national action plans to combat AMR, their implementation has lagged due to resource constraints, dysfunctional multisectoral coordination mechanisms and, importantly, an under-recognized lack of technical capacity to adapt evidence-based AMR mitigation interventions to local contexts. AMR interventions should be tailored, context-specific, cost-effective and sustainable. The implementation and subsequent scale-up of these interventions require multidisciplinary intervention-implementation research (IIR). IIR involves both quantitative and qualitative approaches, occurs across a three-phase continuum (proof of concept, proof of implementation and informing scale-up), and across four context domains (inner setting, outer setting, stakeholders and the implementation process). We describe the theoretical underpinnings of implementation research (IR), its various components, and how to construct different IR strategies to facilitate sustainable uptake of AMR interventions. Additionally, we provide real-world examples of AMR strategies and interventions to demonstrate these principles in practice. IR provides a practical framework to implement evidence-based and sustainable AMR mitigation interventions.

Identifiers

PMID36994233
PMCPMC10041058

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read2
measurements read6
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.