Evidence map›Paper›PMID 36994211›Full record

ArticleFrontiers in oncology2023

Combined biology-guided radiotherapy and Lutetium PSMA theranostics treatment in metastatic castrate-resistant prostate cancer.

Mathieu Gaudreault, David Chang, Nicholas Hardcastle, Price Jackson, Tomas Kron, Michael S Hofman, Shankar Siva

Open access · goldFull text read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mathieu GaudreaultDepartment of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
David ChangSir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.
Nicholas HardcastleDepartment of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Price JacksonDepartment of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Tomas KronDepartment of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Michael S HofmanSir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.
Shankar SivaSir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.
Peter MacCallum Cancer Centre · AUUniversity of Melbourne · AUUniversity of Wollongong · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lutetium-177 [ Materials and methods: All patients excluded from the LuPSMA clinical trial (ID: ANZCTR12615000912583) due to PSMA/FDG discordance were retrospectively reviewed. A hypothetical workflow where PSMA-negative/FDG-positive metastases would be treated with BgRT whilst PSMA-positive metastases would be treated with Lutetium-177 [ Results: In 75 patients screened for Lutetium-177 [ Conclusions: Combined BgRT/Lutetium-177 [

Indexed as

BgRTLuPSMAmCRPCPSMAtheranostics

Identifiers

PMID36994211
PMCPMC10040757
OpenAlexW4324078267

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read36
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.