ReviewSports medicine and health science2023
Chrono-exercise: Time-of-day-dependent physiological responses to exercise.
Review in Sports medicine and health science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06601660 (Effect of Combined Physical Training At Different Times of the Day on Muscle and Adipose Tissue Remodeling, Metabolism and Physical Performance in Female Mice and Women with Obesity), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Combined Physical Training At Different Times of the Day on Muscle and Adipose Tissue Remodeling, Metabolism and Physical Performance in Female Mice and Women with Obesity
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Mapping the effects of exercise on cognition and physical function: a scoping review of rodent studies.Frontiers in physiology · 2026Pooled it
- Within-Day Timing of Concurrent Training Affects Inflammation and Body Composition in Young Adults With Obesity.Obesity (Silver Spring, Md.) · 2026Trial
- Time-of-Day-Specific High-Intensity Interval Training (Chrono-HIIT) in Chinese College Students with Low Physical Activity Levels: Protocol for a Mixed-Methods Feasibility Pilot Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2026Article
- p75NTR Promotes Circadian-Driven Mineralization During Tooth Development via CK2/PER2 Pathway.Cell proliferation · 2026Article
- Afternoon exercise was associated with greater fat loss than morning exercise in overweight/obese adults: an exploratory study of PER3 rs228697 genotype matching.Frontiers in physiology · 2026Article
- Physical exercise as a modulator of the sleep-obesity interaction: metabolic, neuroendocrine and circadian mechanisms.Frontiers in sleep · 2026Review
- Timing-dependent effects of green tea supplementation and exercise intensity on oxidative stress in diabetic rats: a 2 × 2 × 2 factorial study.Frontiers in sports and active living · 2026Article
- Effects of Chrono-Exercise and Chrono-Nutrition on Muscle Health: Understanding the Molecular Mechanisms Activated by Timed Exercise and Consumption of Proteins and Carbohydrates.Nutrition reviews · 2025Review
- Circadian clock dysfunction in Parkinson's disease: mechanisms, consequences, and therapeutic strategy.NPJ Parkinson's disease · 2025Review
- Muscle Rev-erb controls time-dependent adaptations to chronic exercise in mice.Nature communications · 2025Article
- Circadian clock and its effect on aging and lifespan.Biogerontology · 2025Review
- Comparative effectiveness of morning and evening aerobic exercise on weight loss and physical fitness in Chinese college students with overweight and obesity.BMC sports science, medicine & rehabilitation · 2025Article
- The association of activity patterns on female reproductive diseases: a prospective cohort study of UK biobank.BMC public health · 2025Article
- Circadian system and aging: where both times interact.Frontiers in aging · 2025Review
- Temporal patterns of energy intake and physical activity and cross-sectional associations with body weight status in children and adolescents: results from the Portuguese National Food, Nutrition and Physical Activity Survey 2015-2016.The British journal of nutrition · 2024Article
- Sensor-Based Assessment of Time-of-Day-Dependent Physiological Responses and Physical Performances during a Walking Football Match in Higher-Weight Men.Sensors (Basel, Switzerland) · 2024Article
- Climate change impact on blood haemogram in the horse: a three-year preliminary study.Frontiers in veterinary science · 2024Article
- Review
- The effects of physical exercise therapy on weight control: its regulation of adipocyte physiology and metabolic capacity.Journal of exercise rehabilitation · 2023Review
- Exercise Timing Matters for Glycogen Metabolism and Accumulated Fat Oxidation over 24 h.Nutrients · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exercise is an effective strategy to prevent and improve obesity and related metabolic diseases. Exercise increases the metabolic demand in the body. Although many of the metabolic health benefits of exercise depend on skeletal muscle adaptations, exercise exerts many of its metabolic effects through the liver, adipose tissue, and pancreas. Therefore, exercise is the physiological state in which inter-organ signaling is most important. By contrast, circadian rhythms in mammals are associated with the regulation of several physiological and biological functions, including body temperature, sleep-wake cycle, physical activity, hormone secretion, and metabolism, which are controlled by clock genes. Glucose and lipid tolerance reportedly exhibit diurnal variations, being lower in the evening than in the morning. Therefore, the effects of exercise on substrate metabolism at different times of the day may differ. In this review, the importance of exercise timing considerations will be outlined, incorporating a chrono-exercise perspective.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.