Evidence map›Paper›PMID 36993975›Full record

ReviewFrontiers in immunology2023

Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis.

Kangling Zhang, Mark L Sowers, Ellie I Cherryhomes, Vipul K Singh, Abhishek Mishra, Blanca I Restrepo, Arshad Khan, Chinnaswamy Jagannath

Full text readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Epigenetic Reprogramming byAntibiotics (Basel, Switzerland) · 2026
    Review
  5. Review
  6. Review
  7. Observational
  8. Review
  9. Review
  10. Review
  11. Variants in theJournal of clinical tuberculosis and other mycobacterial diseases · 2024
    Article
  12. Article
  13. Epigenetic Mechanisms Induced byInternational journal of molecular sciences · 2024
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kangling ZhangDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX, United States.
Mark L SowersDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX, United States.
Ellie I CherryhomesDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX, United States.
Vipul K SinghDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Weill-Cornell Medicine, Houston, TX, United States.
Abhishek MishraDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Weill-Cornell Medicine, Houston, TX, United States.
Blanca I RestrepoUniversity of Texas Health Houston, School of Public Health, Brownsville, TX, United States.
Arshad KhanDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Weill-Cornell Medicine, Houston, TX, United States.
Chinnaswamy JagannathDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Weill-Cornell Medicine, Houston, TX, United States.

Funding

Novel Stem Cell Immunotherapy for MDR-TuberculosisR01AI161015 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI ENDSLEY, JANICE J, JAGANNATH, CHINNASWAMY · 2021 to 2025
$4.8M
SigH based attenuated, efficacious Mtb vaccines to protect against lethal TBR01AI138587 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI JAGANNATH, CHINNASWAMY, KAUSHAL, DEEPAK · 2018 to 2022
$4.4M
NIAID NIH HHS R01 AI138587NIAID NIH HHS R01 AI161015
6 · The paper itself

Abstract

Macrophages are the preeminent phagocytic cells which control multiple infections. Tuberculosis a leading cause of death in mankind and the causative organism

Indexed as

Anti-Infective AgentsSirtuinsTuberculosisEpigenesis, GeneticHistonesHumansMacrophagesNADReactive Oxygen SpeciesAnti-Infective AgentsHistonesNADReactive Oxygen SpeciesSirtuinsautophagyglycolysishistone modificationshuman macrophagesmetabolismSIRTUIN

Identifiers

PMID36993975
PMCPMC10040548

What OpenQuestion holds

Textfull text, public
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.