Evidence map›Paper›PMID 36993742›Full record

ArticlebioRxiv : the preprint server for biology2023

Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: The METS-Microbiome Study.

Gertrude Ecklu-Mensah, Candice Choo-Kang, Maria Gjerstad Maseng, Sonya Donato, Pascal Bovet, Kweku Bedu-Addo, Jacob Plange-Rhule, Terrence E Forrester, Estelle V Lambert, Dale Rae and 5 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 9 countries.

Gertrude Ecklu-MensahDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Candice Choo-KangPublic Health Sciences, Parkinson School of Health Sciences and Public Health, Loyola University Chicago, Maywood, IL, USA.
Maria Gjerstad MasengInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Sonya DonatoDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Pascal BovetUniversity Center for Primary Care and Public Health (Unisanté), Lausanne, Switzerland& Ministry of Health, Republic of Seychelles Department of Physiology, SMS.
Kweku Bedu-AddoKwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Jacob Plange-RhuleKwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Terrence E ForresterSolutions for Developing Countries, University of the West Indies, Mona, Kingston, Jamaica.
Estelle V LambertResearch Unit for Exercise Science and Sports Medicine, University of Cape Town, Cape Town, South Africa.
Dale RaeResearch Unit for Exercise Science and Sports Medicine, University of Cape Town, Cape Town, South Africa.
Amy LukePublic Health Sciences, Parkinson School of Health Sciences and Public Health, Loyola University Chicago, Maywood, IL, USA.
Brian T LaydenDepartment of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Stephen O'KeefeDepartment of Medicine, University of Pittsburgh, PA, USA.
Jack A GilbertDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Lara R DugasPublic Health Sciences, Parkinson School of Health Sciences and Public Health, Loyola University Chicago, Maywood, IL, USA.
University of California San Diego · USUniversity of Cape Town · ZAKwame Nkrumah University of Science and Technology · GHLoyola University Chicago · USCentre universitaire de médecine générale et santé publique, Lausanne · CHOslo University Hospital · NOUniversity of Illinois Chicago · USUniversity of Pittsburgh · USUniversity of the West Indies System · JM

Funding

Gut microbiota, short chain fatty acids, and adiposity across the epidemiologic transitionR01DK111848 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI DUGAS, LARA RUTH · 2017 to 2021
$3.0M
Illumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600k
NIDDK NIH HHS R01 DK111848NIH HHS S10 OD026929
6 · The paper itself

Abstract

The relationship between the gut microbiota, short chain fatty acid (SCFA) metabolism, and obesity remains unclear due to conflicting reports from studies with limited statistical power. Additionally, this association has rarely been explored in large scale diverse populations. Here, we investigated associations between fecal microbial composition, predicted metabolic potential, SCFA concentrations, and obesity in a large (

Identifiers

PMID36993742
PMCPMC10055249
OpenAlexW4360618312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.