ArticlebioRxiv : the preprint server for biology2023
Arteries are finely tuned thermosensors regulating myogenic tone and blood flow.
Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
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Abstract
In response to changing blood pressure, arteries adjust their caliber to control perfusion. This vital autoregulatory property, termed vascular myogenic tone, stabilizes downstream capillary pressure. We discovered that tissue temperature critically determines myogenic tone. Heating steeply activates tone in skeletal muscle, gut, brain and skin arteries with temperature coefficients ( One-Sentence Summary: Arterial blood pressure and temperature are integrated via thermosensitve ion channels to produce myogenic tone.
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Registered trials
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