Evidence map›Paper›PMID 36993601›Full record

ArticlebioRxiv : the preprint server for biology2023

Coordination of Alternative Splicing and Alternative Polyadenylation revealed by Targeted Long-Read Sequencing.

Zhiping Zhang, Bongmin Bae, Winston H Cuddleston, Pedro Miura

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhiping ZhangDepartment of Biology, University of Nevada, Reno, Reno, NV, USA.
Bongmin BaeDepartment of Biology, University of Nevada, Reno, Reno, NV, USA.
Winston H CuddlestonDepartment of Biology, University of Nevada, Reno, Reno, NV, USA.
Pedro MiuraDepartment of Biology, University of Nevada, Reno, Reno, NV, USA.
University of Nevada, Reno · US

Funding

Virtual Reality and Augmented Reality CoreP20GM103650 · NIGMS · UNIVERSITY OF NEVADA RENO · PI WEBSTER, MICHAEL A · 2012 to 2022
$20.9M
Scope and mechanism of coordinated alternative splicing and alternative polyadenylationR35GM138319 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Pedro Miura · 2020 to 2026
$3.0M
NIGMS NIH HHS P20 GM103650NIGMS NIH HHS R35 GM138319
6 · The paper itself

Abstract

Nervous system development is associated with extensive regulation of alternative splicing (AS) and alternative polyadenylation (APA). AS and APA have been extensively studied in isolation, but little is known about how these processes are coordinated. Here, the coordination of cassette exon (CE) splicing and APA in

Identifiers

PMID36993601
PMCPMC10055423
OpenAlexW4360869673

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.