Evidence map›Paper›PMID 36993597›Full record

ArticlebioRxiv : the preprint server for biology2023

Transitions between cognitive topographies: contributions of network structure, neuromodulation, and disease.

Andrea I Luppi, S Parker Singleton, Justine Y Hansen, Danilo Bzdok, Amy Kuceyeski, Richard F Betzel, Bratislav Misic

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Andrea I LuppiMontréal Neurological Institute, McGill University, Montréal, QC, Canada.
S Parker SingletonDepartment of Computational Biology, Cornell University, Ithaca, NY, U.S.A.
Justine Y HansenMontréal Neurological Institute, McGill University, Montréal, QC, Canada.
Danilo BzdokMontréal Neurological Institute, McGill University, Montréal, QC, Canada.
Amy KuceyeskiDepartment of Radiology, Weill Cornell Medicine, New York, NY, U.S.A.
Richard F BetzelPsychological and Brain Sciences, Indiana University, Bloomington, IN, U.S.A.
Bratislav MisicMontréal Neurological Institute, McGill University, Montréal, QC, Canada.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
Multi-Modal Imaging of the Mechanisms Underlying Impaired Executive Attention After Traumatic Brain InjuryR01NS102646 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI KUCEYESKI, AMY FRANCES, SHAH, SUDHIN · 2018 to 2022
$2.8M
Investigating the impact of loneliness on brain aging and pre-symptomatic Alzheimer's disease progressionR01AG068563 · NIA · MCGILL UNIVERSITY · PI BZDOK, DANILO, SPRENG, ROBERT NATHAN · 2020 to 2024
$2.3M
Application of a Bayesian strategy to ABCD: Identification of substance use risk and COVID-19 effects on neurodevelopmentR01DA053301 · NIDA · YALE UNIVERSITY · PI Sarah Yip · 2022 to 2026
$1.6M
Heritability and cognitive implications of structural-functional connectome couplingRF1MH123232 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI KUCEYESKI, AMY FRANCES · 2021 to 2021
$1.3M
Quantifying the role of the connectome in resiliency to multiple sclerosisR21NS104634 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI KUCEYESKI, AMY FRANCES · 2017 to 2018
$466k
NIA NIH HHS R01 AG068563NIDA NIH HHS R01 DA053301NIMH NIH HHS RF1 MH123232NIMH NIH HHS U54 MH091657NINDS NIH HHS R01 NS102646NINDS NIH HHS R21 NS104634
6 · The paper itself

Abstract

Patterns of neural activity underlie human cognition. Transitions between these patterns are orchestrated by the brain's network architecture. What are the mechanisms linking network structure to cognitively relevant activation patterns? Here we implement principles of network control to investigate how the architecture of the human connectome shapes transitions between 123 experimentally defined cognitive activation maps (cognitive topographies) from the NeuroSynth meta-analytic engine. We also systematically incorporate neurotransmitter receptor density maps (18 receptors and transporters) and disease-related cortical abnormality maps (11 neurodegenerative, psychiatric and neurodevelopmental diseases;

Identifiers

PMID36993597
PMCPMC10055141

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.