Evidence map›Paper›PMID 36993508›Full record

ArticlebioRxiv : the preprint server for biology2023

Hardwired to attack: Transcriptionally defined amygdala subpopulations play distinct roles in innate social behaviors.

Julieta E Lischinsky, Luping Yin, Chenxi Shi, Nandkishore Prakash, Jared Burke, Govind Shekaran, Maria Grba, Joshua G Corbin, Dayu Lin

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Julieta E LischinskyNeuroscience Institute, New York University School of Medicine, New York, NY, USA.
Luping YinNeuroscience Institute, New York University School of Medicine, New York, NY, USA.
Chenxi ShiNeuroscience Institute, New York University School of Medicine, New York, NY, USA.
Nandkishore PrakashCenter for Neuroscience Research, Children's National Hospital, Washington, DC, United States.
Jared BurkeNeuroscience Institute, New York University School of Medicine, New York, NY, USA.
Govind ShekaranNeuroscience Institute, New York University School of Medicine, New York, NY, USA.
Maria GrbaNeuroscience Institute, New York University School of Medicine, New York, NY, USA.
Joshua G CorbinCenter for Neuroscience Research, Children's National Hospital, Washington, DC, United States.
Dayu LinNeuroscience Institute, New York University School of Medicine, New York, NY, USA.
New York University · USJefferson Hospital for Neuroscience · USHunter College · US

Funding

U19 Supplement 2023-FroemkeU19NS107616 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Adam Christopher Mar · 2018 to 2026
$36.4M
Research Supplement to Promote Diversity in Health-Related ResearchR01MH101377 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Dayu Lin · 2013 to 2026
$8.6M
Development of the Basal Telencephalic Limbic SystemR01DA020140 · NIDA · GEORGETOWN UNIVERSITY · PI CORBIN, JOSHUA G · 2006 to 2020
$7.3M
The Neural Mechanisms of Winner and Loser EffectR01MH124927 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Dayu Lin · 2022 to 2026
$3.1M
Dissecting the neural circuits of maternal behaviorsR01HD092596 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LIN, DAYU · 2018 to 2022
$2.4M
Cellular and transcriptomic programs linking amygdala progenitors to mature neuronal identityR21MH129995 · NIMH · CHILDREN'S RESEARCH INSTITUTE · PI CORBIN, JOSHUA G, HAYDAR, TARIK F · 2022 to 2023
$594k
Developmental and circuit mechanisms for innate social behaviors in the medial amygdalaK99MH127295 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LISCHINSKY, JULIETA E · 2021 to 2022
$261k
NICHD NIH HHS R01 HD092596NIDA NIH HHS R01 DA020140NIMH NIH HHS K99 MH127295NIMH NIH HHS R01 MH101377NIMH NIH HHS R01 MH124927NIMH NIH HHS R21 MH129995NINDS NIH HHS U19 NS107616
6 · The paper itself

Abstract

Social behaviors are innate and supported by dedicated neural circuits, but it remains unclear whether these circuits are developmentally hardwired or established through social experience. Here, we revealed distinct response patterns and functions in social behavior of medial amygdala (MeA) cells originating from two embryonically parcellated developmental lineages. MeA cells in male mice that express the transcription factor Foxp2 (MeA

Identifiers

PMID36993508
PMCPMC10055059
OpenAlexW4327862105

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.