Evidence map›Paper›PMID 36993499›Full record

ArticlebioRxiv : the preprint server for biology2023

FRS2-independent GRB2 interaction with FGFR2 is not required for embryonic development.

James F Clark, Philippe Soriano

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

James F ClarkDepartment of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
Philippe SorianoDepartment of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
Icahn School of Medicine at Mount Sinai · US

Funding

FGF Signaling Pathways and Craniofacial DevelopmentR01DE022778 · NIDCR · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SORIANO, PHILIPPE M · 2012 to 2022
$6.6M
Novel Effectors of FGF Signaling in Craniofacial DevelopmentF32DE029387 · NIDCR · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CLARK, JAMES · 2020 to 2022
$208k
NIDCR NIH HHS F32 DE029387NIDCR NIH HHS R01 DE022778
6 · The paper itself

Abstract

FGF activation is known to engage canonical signals, including ERK/MAPK and PI3K/AKT, through various effectors including FRS2 and GRB2.

Identifiers

PMID36993499
PMCPMC10055321
OpenAlexW4360943971

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.