Evidence map›Paper›PMID 36993349›Full record

ArticlebioRxiv : the preprint server for biology2023

Reciprocal discoidin domain receptor signaling strengthens integrin adhesion to connect adjacent tissues.

Kieop Park, Ranjay Jayadev, Sara G Payne, Isabel W Kenny-Ganzert, Qiuyi Chi, Daniel S Costa, William Ramos-Lewis, Siddharthan Balachandar Thendral, David R Sherwood

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kieop ParkDepartment of Biology, Duke University, Box 90338, Durham, NC 27708, USA.ORCID 0000-0002-6380-4730
Ranjay JayadevDepartment of Biology, Duke University, Box 90338, Durham, NC 27708, USA.ORCID 0000-0003-0465-0337
Sara G PayneDepartment of Biology, Duke University, Box 90338, Durham, NC 27708, USA.ORCID 0000-0002-3572-9112
Isabel W Kenny-GanzertDepartment of Biology, Duke University, Box 90338, Durham, NC 27708, USA.ORCID 0000-0001-6306-4472
Qiuyi ChiDepartment of Biology, Duke University, Box 90338, Durham, NC 27708, USA.ORCID 0000-0003-1297-4163
Daniel S CostaDepartment of Biology, Duke University, Box 90338, Durham, NC 27708, USA.ORCID 0000-0003-2179-8800
William Ramos-LewisDepartment of Biology, Duke University, Box 90338, Durham, NC 27708, USA.ORCID 0000-0002-4627-4571
Siddharthan Balachandar ThendralDepartment of Biology, Duke University, Box 90338, Durham, NC 27708, USA.ORCID 0000-0002-4674-7033
David R SherwoodDepartment of Biology, Duke University, Box 90338, Durham, NC 27708, USA.ORCID 0000-0002-4448-6917
Duke University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Understanding how cells invade through basement membrane in vivoR35GM118049 · NIGMS · DUKE UNIVERSITY · PI David R Sherwood · 2016 to 2026
$6.8M
A comprehensive toolkit to visualize endogenously tagged fluorescent basement membrane components in a living animalR21OD028766 · OD · DUKE UNIVERSITY · PI SHERWOOD, DAVID R · 2020 to 2021
$427k
A Comprehensive Endogenous Basement Membrane Toolkit to Elucidate how Basement Membranes Stretch on Mechanically Active Tissues and Decline during AgingR21OD032430 · OD · DUKE UNIVERSITY · PI SHERWOOD, DAVID R · 2022 to 2023
$427k
Understanding the role of the collagen receptor DDR-2 in germ stem cell niche formationF31HD097901 · NICHD · DUKE UNIVERSITY · PI PAYNE, SARA GRACE · 2019 to 2021
$112k
NICHD NIH HHS F31 HD097901NIGMS NIH HHS R35 GM118049NIH HHS P40 OD010440NIH HHS R21 OD028766NIH HHS R21 OD032430
6 · The paper itself

Abstract

Separate tissues connect through adjoining basement membranes to carry out molecular barrier, exchange, and organ support functions. Cell adhesion at these connections must be robust and balanced to withstand independent tissue movement. Yet, how cells achieve synchronized adhesion to connect tissues is unknown. Here, we have investigated this question using the

Identifiers

PMID36993349
PMCPMC10055161
OpenAlexW4324347390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.