Evidence map›Paper›PMID 36993318›Full record

ArticlebioRxiv : the preprint server for biology2023

An improved rhythmicity analysis method using Gaussian Processes detects cell-density dependent circadian oscillations in stem cells.

Shabnam Sahay, Shishir Adhikari, Sahand Hormoz, Shaon Chakrabarti

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Shabnam SahayDepartment of Computer Science, Indian Institute of Technology Bombay.
Shishir AdhikariDepartment of Systems Biology, Harvard Medical School, Boston.
Sahand HormozDepartment of Systems Biology, Harvard Medical School, Boston.
Shaon ChakrabartiSimons Centre for the Study of Living Machines, National Centre for Biological Sciences, Bangalore.

Funding

Tracing the lineage histories and differentiation trajectories of individual cancer cells in myeloproliferative neoplasmsR01HL158269 · NHLBI · DANA-FARBER CANCER INST · PI HORMOZ, SAHAND · 2021 to 2025
$2.3M
NHLBI NIH HHS R01 HL158269
6 · The paper itself

Abstract

Detecting oscillations in time series remains a challenging problem even after decades of research. In chronobiology, rhythms in time series (for instance gene expression, eclosion, egg-laying and feeding) datasets tend to be low amplitude, display large variations amongst replicates, and often exhibit varying peak-to-peak distances (non-stationarity). Most currently available rhythm detection methods are not specifically designed to handle such datasets. Here we introduce a new method, ODeGP (

Identifiers

PMID36993318
PMCPMC10055182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.