Evidence map›Paper›PMID 36993291›Full record

ArticlebioRxiv : the preprint server for biology2023

Parasite hybridization promotes spreading of endosymbiotic viruses.

Senne Heeren, Ilse Maes, Mandy Sanders, Lon-Fye Lye, Jorge Arevalo, Alejandro Llanos-Cuentas, Lineth Garcia, Philippe Lemey, Stephen M Beverley, James A Cotton and 2 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 5 countries.

Senne HeerenDepartment of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Ilse MaesDepartment of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Mandy SandersParasite Genomics Group, Welcome Sanger Institute, Hinxton, United Kingdom.
Lon-Fye LyeDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, United States.
Jorge ArevaloInstituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.
Alejandro Llanos-CuentasInstituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.
Lineth GarciaInstituto de Investigación Biomédicas e Investigación Social, Universidad Mayor de San Simon, Cochabamba, Bolivia.
Philippe LemeyDepartment of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium.
Stephen M BeverleyDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, United States.
James A CottonParasite Genomics Group, Welcome Sanger Institute, Hinxton, United Kingdom.
Jean-Claude DujardinDepartment of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Frederik Van den BroeckDepartment of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Rega Institute for Medical Research · BEUniversidad Peruana Cayetano Heredia · PEUniversity of Antwerp · BEWashington University in St. Louis · USWellcome Sanger Institute · GBInstituut voor Tropische Geneeskunde · BEUniversidad Mayor de San Simón · BO

Funding

MOLECULAR GENETICS OF LEISHMANIA USING DNA TRANSFECTIONR01AI029646 · NIAID · WASHINGTON UNIVERSITY · PI BEVERLEY, STEPHEN M · 1990 to 2015
$9.3M
Leishmania RNA viruses and pathogenesisR01AI130222 · NIAID · WASHINGTON UNIVERSITY · PI BEVERLEY, STEPHEN M · 2018 to 2022
$3.3M
NIAID NIH HHS R01 AI029646NIAID NIH HHS R01 AI130222
6 · The paper itself

Abstract

Viruses are the most abundant biological entities on Earth and play a significant role in the evolution of many organisms and ecosystems. In pathogenic protozoa, the presence of endosymbiotic viruses has been linked to an increased risk of treatment failure and severe clinical outcome. Here, we studied the molecular epidemiology of the zoonotic disease cutaneous leishmaniasis in Peru and Bolivia through a joint evolutionary analysis of

Identifiers

PMID36993291
PMCPMC10055345
OpenAlexW4360942569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.