Evidence map›Paper›PMID 36993207›Full record

ArticlebioRxiv : the preprint server for biology2023

The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in

Felicity J Emerson, Caitlin Chiu, Laura Y Lin, Christian G Riedel, Ming Zhu, Siu Sylvia Lee

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Felicity J EmersonDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America.
Caitlin ChiuDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America.
Laura Y LinDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America.
Christian G RiedelDepartment of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.
Ming ZhuNational Institute of Biological Sciences, Beijing, China.
Siu Sylvia LeeDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America.
Cornell University · USKarolinska Institutet · SENational Institute of Biological Sciences, Beijing · CN

Funding

Systematic Analysis of C elegans Longevity DeterminantsR01AG024425 · NIA · CORNELL UNIVERSITY ITHACA · PI Siu Sylvia Lee · 2004 to 2026
$8.5M
NIA NIH HHS R01 AG024425
6 · The paper itself

Abstract

SET-26, HCF-1, and HDA-1 are highly conserved chromatin factors with key roles in development and aging. Here we present mechanistic insights into how these factors regulate gene expression and modulate longevity in

Identifiers

PMID36993207
PMCPMC10055255
OpenAlexW4360603188

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.