Evidence map›Paper›PMID 36993167›Full record

ArticlebioRxiv : the preprint server for biology2023

A CUG-initiated CATSPERθ functions in the CatSper channel assembly and serves as a checkpoint for flagellar trafficking.

Xiaofang Huang, Haruhiko Miyata, Huafeng Wang, Giulia Mori, Rie Iida-Norita, Masahito Ikawa, Riccardo Percudani, Jean-Ju Chung

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Xiaofang HuangDepartment of Cellular and Molecular Physiology, Yale School of Medicine, Yale University, New Haven, CT, 06510, USA.
Haruhiko MiyataResearch Institute for Microbial Diseases, Osaka University, Suita 5650871, Japan.
Huafeng WangDepartment of Cellular and Molecular Physiology, Yale School of Medicine, Yale University, New Haven, CT, 06510, USA.
Giulia MoriDepartment of Chemistry, Life sciences, and Environmental Sustainability, University of Parma, Parma 43124, Italy.
Rie Iida-NoritaResearch Institute for Microbial Diseases, Osaka University, Suita 5650871, Japan.
Masahito IkawaResearch Institute for Microbial Diseases, Osaka University, Suita 5650871, Japan.
Riccardo PercudaniDepartment of Chemistry, Life sciences, and Environmental Sustainability, University of Parma, Parma 43124, Italy.
Jean-Ju ChungDepartment of Cellular and Molecular Physiology, Yale School of Medicine, Yale University, New Haven, CT, 06510, USA.

Funding

Targeting sperm-specific proteins during meiosis and sperm morphogenesisP01HD087157 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI GARCIA, THOMAS · 2017 to 2021
$6.2M
Functional analysis of novel testis-expressed secreted and transmembrane proteinsR01HD088412 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MARTIN M. MATZUK · 2016 to 2026
$4.5M
CatSper regulation of sperm physiology and fertilityR01HD096745 · NICHD · YALE UNIVERSITY · PI Jean-Ju Lucia Chung · 2019 to 2026
$3.4M
NICHD NIH HHS P01 HD087157NICHD NIH HHS R01 HD088412NICHD NIH HHS R01 HD096745
6 · The paper itself

Abstract

Calcium signaling is critical for successful fertilization. In spermatozoa, calcium influx into the sperm flagella mediated by the sperm specific CatSper calcium channel is necessary for hyperactivated motility and male fertility. CatSper is a macromolecular complex and is repeatedly arranged in zigzag rows within four linear nanodomains along the sperm flagella. Here, we report that the

Identifiers

PMID36993167
PMCPMC10055175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.