Evidence map›Paper›PMID 36993120›Full record

ArticleJournal of family medicine and primary care2022

Thyrotoxic hypokalemic periodic paralysis and COVID-19 infection.

Sitanun Chinangkulpiwat, Jutamart Tantiprawan, Jakkrit Amornvit, Patchaya Bunchaya-Anant, Thiti Snabboon

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of family medicine and primary care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sitanun ChinangkulpiwatDepartment of Medicine, Bang Phli Hospital, Samut Prakan Province, Bangkok, Thailand.
Jutamart TantiprawanDepartment of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Jakkrit AmornvitDepartment of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Patchaya Bunchaya-AnantDepartment of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Thiti SnabboonDepartment of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Chulalongkorn University · THThai Red Cross Society · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various conditions causing weakness associated with coronavirus disease 2019 (COVID-19) infection have been described, including cerebrovascular diseases, acute myelitis, Guillain-Barré syndrome, myasthenia gravis, critical illness myopathy and neuropathy, myositis, and rhabdomyolysis. We report an adult man presenting with an unusual etiology of weakness after a COVID-19 infection. Thyrotoxic hypokalemic periodic paralysis (THPP) was diagnosed from the presence of Graves' disease and hypokalemia because of intra-cellular potassium shifting. His weakness and hypokalemia responded well to potassium supplements and a non-selective b-blocker, whereas his thyrotoxicosis was initially controlled by an anti-thyroid medication and subsequently with radioactive iodine therapy. He was also treated as having mild COVID-19 based on his normal chest X-ray and oxygenation level. This is the first report showing an association between COVID-19 infection and a paralysis attack of THPP. Physicians should be alerted about this unusual cause of weakness, particularly in Asian patients.

Indexed as

COVID-19diseaseGraves’hypokalemiaperiodic paralysisthyrotoxicosis

Identifiers

PMID36993120
PMCPMC10041286
OpenAlexW4313209639

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.