Evidence map›Paper›PMID 36992830›Full record

ArticleFrontiers in pharmacology2023

Dose adjustment not required for contezolid in patients with moderate hepatic impairment based on pharmacokinetic/pharmacodynamic analysis.

Junzhen Wu, Xinyi Yang, Jufang Wu, Jingjing Wang, Hailan Wu, Yu Wang, Hong Yuan, Huahui Yang, Hailin Wang, Jing Zhang

Open access · goldFull text read
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Contezolid in tuberculosis therapy: a retrospective analysis of real-world practice in China.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Junzhen WuPhase I Unit, Huashan Hospital, Fudan University, Shanghai, China.
Xinyi YangPhase I Unit, Huashan Hospital, Fudan University, Shanghai, China.
Jufang WuPhase I Unit, Huashan Hospital, Fudan University, Shanghai, China.
Jingjing WangPhase I Unit, Huashan Hospital, Fudan University, Shanghai, China.
Hailan WuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Yu WangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Hong YuanInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Huahui YangShanghai MicuRx Pharmaceutical Co., Ltd., Shanghai, China.
Hailin WangShanghai MicuRx Pharmaceutical Co., Ltd., Shanghai, China.
Jing ZhangPhase I Unit, Huashan Hospital, Fudan University, Shanghai, China.
Fudan University · CNHuashan Hospital · CNNational Health and Family Planning Commission · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

contezoliddose adjustmentdosing regimenhepatic impairmentpharmacokinetic/pharmacodynamic analysissafety

Identifiers

PMID36992830
PMCPMC10040594
OpenAlexW4324087303

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read4
measurements read67
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.