Evidence map›Paper›PMID 36992824›Full record

ArticleDiagnostic and interventional radiology (Ankara, Turkey)2023

Inversed albumin-to-globulin ratio and underlying liver disease severity as a prognostic factor for survival in hepatocellular carcinoma patients undergoing transarterial chemoembolization.

Jinlong Li, Zhi Li, Shirui Hao, Jitao Wang, Wei Chen, Shoufang Dai, Zhenguo Hou, Borun Chen, Yewei Zhang, Dengxiang Liu

Open access · goldAbstract read
In one paragraph

Article in Diagnostic and interventional radiology (Ankara, Turkey), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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  3. [Establishment of a Noninvasive Diagnostic Model for Wilson Disease Using Metallomics and Machine Learning].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jinlong LiXingtai Institute of Cancer Control, Xingtai People's Hospital, Hebei, China.ORCID 0000-0001-9752-8554
Zhi LiDepartment of Infection Management, Xingtai General Hospital of North China Healthcare Group, Hebei, China.ORCID 0000-0002-8080-8055
Shirui HaoXingtai Institute of Cancer Control, Xingtai People's Hospital, Hebei, China.ORCID 0000-0001-5594-9019
Jitao WangXingtai Institute of Cancer Control, Xingtai People's Hospital, Hebei, China.ORCID 0000-0002-3071-494X
Wei ChenXingtai Institute of Cancer Control, Xingtai People's Hospital, Hebei, China.ORCID 0000-0001-9736-4588
Shoufang DaiXingtai Institute of Cancer Control, Xingtai People's Hospital, Hebei, China.ORCID 0000-0003-0816-9807
Zhenguo HouXingtai Institute of Cancer Control, Xingtai People's Hospital, Hebei, China.ORCID 0000-0002-7689-6478
Borun ChenXingtai Institute of Cancer Control, Xingtai People's Hospital, Hebei, China.ORCID 0000-0002-8072-3924
Yewei ZhangDepartment of Infection Management, Xingtai General Hospital of North China Healthcare Group, Hebei, China.ORCID 0000-0002-0405-0844
Dengxiang LiuXingtai Institute of Cancer Control, Xingtai People's Hospital, Hebei, China.ORCID 0000-0003-4047-1379
Hebei Medical University · CNXingtai People's Hospital · CNSoutheast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrevious studies have shown that an inversed albumin-to-globulin ratio (IAGR) is a predictor of the prognosis of many cancers. However, the prognostic value of an IAGR for patients with hepatocellular carcinoma (HCC) who undergo transarterial chemoembolization (TACE) is still unclear. This study aims to evaluate the predictive value of an IAGR for the prognosis of those patients.

methodsThis study retrospectively analyzed 396 patients with HCC who received TACE. Using a cut-off value of 1.0 for the albumin-to-globulin ratio, patients were divided into a normal albumin-to-globulin ratio (NAGR) (≥1) and an IAGR (<1) group. Univariate and multivariate analyses and time-dependent receiver operating characteristic analyses were performed to identify risk factors of overall survival (OS) and cancer-specific survival (CSS). Survival nomograms were constructed based on the multivariable analysis results and further evaluated using the consistency index (C-index) and calibration curve.

resultsA total of 396 patients were included in the final analysis and were divided into the NAGR group (n = 298, 75.3%) and the IAGR (n = 98, 24.7%) group. The median OS and CSS were significantly worse in the IAGR group than in the NAGR group (OS: 8 vs. 26 months, CSS: 10 vs. 41 months, both

conclusionThe IAGR along with underlying liver disease severity were the useful prognostic predictors of OS and CSS among patients with HCC undergoing TACE and might be useful to identify high-risk patients.

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticGlobulinsLiver NeoplasmsAlbuminsHumansPatient AcuityPrognosisRetrospective StudiesAlbuminsGlobulinsalbumin-to-globulin ratiocancer-specific survivalHepatocellular carcinomaoverall survivaltransarterial chemoembolization

Identifiers

PMID36992824
PMCPMC10679613
OpenAlexW4315703355

What OpenQuestion holds

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.