Evidence map›Paper›PMID 36992626›Full record

ArticleDiagnostic and interventional radiology (Ankara, Turkey)2023

Thermal ablation of ultrasound and non-contrast computed tomography invisible primary and secondary liver tumors: targeting by selective intra-arterial lipiodol injection.

Adrian Kobe, Lambros Tselikas, Frédéric Deschamps, Charles Roux, Alexandre Delpla, Eloi Varin, Antoine Hakime, Thierry de Baère

Open access · diamondAbstract read
In one paragraph

Article in Diagnostic and interventional radiology (Ankara, Turkey), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Adrian KobeDepartment of Interventional Radiology, Gustave Roussy-Cancer Center, Villejuif, France.ORCID 0000-0002-8931-7412
Lambros TselikasDepartment of Interventional Radiology, Gustave Roussy-Cancer Center, Villejuif, France.ORCID 0000-0002-8878-4916
Frédéric DeschampsDepartment of Interventional Radiology, Gustave Roussy-Cancer Center, Villejuif, France.ORCID 0000-0002-6015-4349
Charles RouxDepartment of Interventional Radiology, Gustave Roussy-Cancer Center, Villejuif, France.ORCID 0000-0002-9584-3048
Alexandre DelplaDepartment of Interventional Radiology, Gustave Roussy-Cancer Center, Villejuif, France.ORCID 0000-0003-4885-4366
Eloi VarinDepartment of Interventional Radiology, Gustave Roussy-Cancer Center, Villejuif, France.ORCID 0000-0002-2399-7064
Antoine HakimeDepartment of Interventional Radiology, Gustave Roussy-Cancer Center, Villejuif, France.ORCID 0000-0002-0546-9786
Thierry de BaèreDepartment of Interventional Radiology, Gustave Roussy-Cancer Center, Villejuif, France.ORCID 0000-0002-4556-7663
Institut Gustave Roussy · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the technical feasibility and outcomes of thermal ablation following selective intra-arterial lipiodol injection (SIALI) for targeting primary and secondary liver tumors invisible on ultrasound (US) and non-contrast computed tomography (CT).

methodsThis retrospective study included 18 patients with 20 tumors (67% male, mean age 60.8 ± 12.1 years). The 20 tumors included 15 liver metastases and 5 hepatocellular carcinomas. All patients underwent single-session SIALI and subsequent CT-guided thermal ablation. The primary outcome was a technical success, defined as visualization of the tumor after SIALI and successful thermal ablation. Secondary outcomes were local recurrence rate and procedure-related complications.

resultsThe median tumor size was 1.5 (1-2.5) cm. In addition, SIALI was performed with a median volume of 3 (1-10) mL of lipiodol resulting in intra-tumoral iodized oil accumulation in 19 tumors and negative imprint with iodized oil accumulation of the surrounding liver parenchyma in 1 tumor. The technical success rate was 100%. No local occurrence was observed at a mean follow-up time of 3 ± 2.5 years.

conclusionSIALI to tag liver tumors not visible with US and non-contrast CT before percutaneous ablation is highly feasible and has a high success rate for the treatment of both primary and secondary liver tumors.

Indexed as

Carcinoma, HepatocellularCatheter AblationLiver NeoplasmsAgedEthiodized OilFemaleHumansMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedEthiodized OilHCCinvisible tumorliver metastasesselective intra-arterial lipiodol injectionthermal ablation

Identifiers

PMID36992626
PMCPMC10679642
OpenAlexW4315866536

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.