Evidence map›Paper›PMID 36992460›Full record

Observational studyViruses2023

SARS-CoV-2 Antibody Response and Sustainability after a Third Dose of BNT162b2 in Healthcare Workers at Health Promotion Centers.

Eun-Hee Nah, Seon Cho, Hyeran Park, Suyoung Kim, Dongwon Noh, Eunjoo Kwon, Han-Ik Cho

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Eun-Hee NahDepartment of Laboratory Medicine and Health Promotion Research Institute, Korea Association of Health Promotion, Seoul 07572, Republic of Korea.ORCID 0000-0003-0637-4364
Seon ChoDepartment of Laboratory Medicine and Health Promotion Research Institute, Korea Association of Health Promotion, Seoul 07572, Republic of Korea.
Hyeran ParkDepartment of Laboratory Medicine and Health Promotion Research Institute, Korea Association of Health Promotion, Seoul 07572, Republic of Korea.
Suyoung KimDepartment of Laboratory Medicine and Health Promotion Research Institute, Korea Association of Health Promotion, Seoul 07572, Republic of Korea.
Dongwon NohDepartment of Laboratory Medicine and Health Promotion Research Institute, Korea Association of Health Promotion, Seoul 07572, Republic of Korea.
Eunjoo KwonDepartment of Laboratory Medicine and Health Promotion Research Institute, Korea Association of Health Promotion, Seoul 07572, Republic of Korea.
Han-Ik ChoMEDIcheck LAB, Korea Association of Health Promotion, Seoul 07572, Republic of Korea.
Korea Association of Health Promotion · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to determine the antibody response and the sustainability of immunogenicity after a third dose of BNT162b2 (BNT) in homologous [ChAdOx1 (ChAd)/ChAd, BNT/BNT, and mRNA-1273 (Moderna)/Moderna] and heterologous (ChAd/BNT) vaccinations of two primary doses with different schemes. This prospective observational study recruited consenting healthcare workers from 16 health checkup centers in 13 Korean cities. Three-point blood tests were analyzed as the antibody response after the third vaccination: T3-1 (1 month after the third dose), T3-3 (3 months after the third dose), and T3-4-10 (4-10 months after the third dose). SARS-CoV-2 antibodies were measured using a chemiluminescence microparticle immunoassay with SARS-CoV-2 IgG II Quant in the ARCHITECT system (Abbott Diagnostics). The antibody levels were significantly higher in the Moderna /Moderna and BNT/BNT groups than in the ChAd/ ChAd and ChAd/BNT groups (

Indexed as

BNT162 VaccineCOVID-19Antibodies, ViralAntibody FormationHealth PersonnelHealth PromotionHumansImmunoglobulin GmRNA VaccinesSARS-CoV-2VaccinationAntibodies, ViralBNT162 VaccineImmunoglobulin GmRNA Vaccinesanti-spike-protein receptor-binding domain (S-RBD) antibodiesmRNA vaccinesSARS-CoV-2third dosevaccination

Identifiers

PMID36992460
PMCPMC10055753
OpenAlexW4324383271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.