Evidence map›Paper›PMID 36992371›Full record

ArticleViruses2023

Growth Velocity and Nutritional Status in Children Exposed to Zika Virus during Pregnancy from Amazonas Cohort, Brazil.

Lucíola de Fátima Albuquerque de Almeida Peixoto, Marília Rosa Abtibol-Bernardino, Cecilia Victoria Caraballo Guerra, Geruza Alfaia de Oliveira, Beatriz Caroline Soares Chaves, Cristina de Souza Rodrigues, Anny Beatriz Costa Antony de Andrade, Elijane de Fátima Redivo, Salete Sara Alvarez Fernandes, Rodrigo Haruo Otani and 10 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Lucíola de Fátima Albuquerque de Almeida PeixotoPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.ORCID 0000-0003-4310-2165
Marília Rosa Abtibol-BernardinoPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.ORCID 0000-0003-4093-226X
Cecilia Victoria Caraballo GuerraPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.
Geruza Alfaia de OliveiraTropical Medicine Foundation Dr. Heitor Vieira Dourado, Manaus 69040-000, Brazil.
Beatriz Caroline Soares ChavesPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.
Cristina de Souza RodriguesPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.
Anny Beatriz Costa Antony de AndradeLeônidas & Maria Deane Institute, ILMD/FIOCRUZ Amazonia, Manaus 69057-070, Brazil.ORCID 0000-0002-7041-620X
Elijane de Fátima RedivoPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.ORCID 0000-0001-8873-1032
Salete Sara Alvarez FernandesPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.
Rodrigo Haruo OtaniSchool of Health Sciences, University of Amazonas State, Manaus 69065-001, Brazil.ORCID 0000-0002-8908-2190
Alexandre Vilhena da Silva NetoPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.
Antônio Alcirley da Silva BalieiroTropical Medicine Foundation Dr. Heitor Vieira Dourado, Manaus 69040-000, Brazil.ORCID 0000-0003-0358-3371
Celso Rômulo Barbosa CabralDepartment of Maternal and Child Health, Medical School, Federal University of Amazonas, Manaus 69020-160, Brazil.
Djane Baia-da-SilvaPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.
Márcia da Costa CastilhoTropical Medicine Foundation Dr. Heitor Vieira Dourado, Manaus 69040-000, Brazil.ORCID 0000-0002-8529-4022
Camila Helena Bôtto-MenezesPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.ORCID 0000-0001-6867-4931
Maria das Graças Costa AlecrimPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.
Maria do Carmo LealLeônidas & Maria Deane Institute, ILMD/FIOCRUZ Amazonia, Manaus 69057-070, Brazil.
Silvana Gomes BenzecrySchool of Health Sciences, University of Amazonas State, Manaus 69065-001, Brazil.
Flor Ernestina Martinez-EspinosaPostgraduate Program in Tropical Medicine (PPGMT), State University of Amazonas (UEA) in Partnership with the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.ORCID 0000-0002-0325-3674
Fundação de Medicina Tropical · BRFundação Oswaldo Cruz · BRUniversidade do Estado do Amazonas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high incidence of Zika virus (ZIKV) infection in the period of 2015-2016 in Brazil may have affected linear height growth velocity (GV) in children exposed in utero to ZIKV. This study describes the growth velocity and nutritional status based on the World Organization (WHO) standards of children exposed to ZIKV during pregnancy and followed up in a tertiary unit, a reference for tropical and infectious diseases in the Amazon. Seventy-one children born between March 2016 and June 2018 were monitored for anthropometric indices: z-score for body mass index (BMI/A); weight (W/A); height (H/A) and head circumference (HC/A); and growth velocity. The mean age at the last assessment was 21.1 months (SD ± 8.93). Four children had congenital microcephaly and severe neurological impairment. The other 67 were non-microcephalic children (60 normocephalic and 7 macrocephalic); of these; 24.2% (16 children) had neurological alterations, and 28.8% (19 children) had altered neuropsychomotor development. Seventeen (24.2%) children had inadequate GV (low growth velocity). The frequencies of low growth among microcephalic and non-microcephalic patients are 25% (1 of 4 children) and 23.9% (16 of 67 children); respectively. Most children had normal BMI/A values during follow-up. Microcephalic patients showed low H/A and HC/A throughout the follow-up, with a significant reduction in the HC/A z-score. Non-microcephalic individuals are within the regular ranges for H/A; HC/A; and W/A, except for the H/A score for boys. This study showed low growth velocity in children with and without microcephaly, highlighting the need for continuous evaluation of all children born to mothers exposed to ZIKV during pregnancy.

Indexed as

MicrocephalyPregnancy Complications, InfectiousZika VirusZika Virus InfectionBrazilChildFemaleHumansInfantMaleNutritional StatusPregnancyanthropometryarboviruschild growthcongenital Zika virus syndromegrowth velocityinfant nutritionnon-microcephalic childrenZika virus

Identifiers

PMID36992371
PMCPMC10056230
OpenAlexW4322741960

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.