Evidence map›Paper›PMID 36992367›Full record

ArticleViruses2023

Rapid Shift from SARS-CoV-2 Delta to Omicron Sub-Variants within a Dynamic Southern U.S. Borderplex.

Elisa Robles-Escajeda, Jonathon E Mohl, Lisett Contreras, Ana P Betancourt, Bibiana M Mancera, Robert A Kirken, Georgialina Rodriguez

Abstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Wastewater Surveillance of SARS-CoV-2 in Zambia: An Early Warning Tool.International journal of molecular sciences · 2024
    Article
  4. Article
  5. Sensitive detection of SARS-CoV-2 main protease 3CLProtein science : a publication of the Protein Society · 2024
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elisa Robles-EscajedaThe Department of Biological Sciences, The University of Texas at El Paso, 500 W. University Ave, El Paso, TX 79968, USA.ORCID 0000-0002-0104-2857
Jonathon E MohlBorder Biomedical Research Center, The University of Texas at El Paso, 500 W. University Ave, El Paso, TX 79968, USA.ORCID 0000-0003-4440-4608
Lisett ContrerasThe Department of Biological Sciences, The University of Texas at El Paso, 500 W. University Ave, El Paso, TX 79968, USA.ORCID 0000-0002-7433-8413
Ana P BetancourtThe Department of Biological Sciences, The University of Texas at El Paso, 500 W. University Ave, El Paso, TX 79968, USA.
Bibiana M ManceraBorder Biomedical Research Center, The University of Texas at El Paso, 500 W. University Ave, El Paso, TX 79968, USA.
Robert A KirkenThe Department of Biological Sciences, The University of Texas at El Paso, 500 W. University Ave, El Paso, TX 79968, USA.
Georgialina RodriguezThe Department of Biological Sciences, The University of Texas at El Paso, 500 W. University Ave, El Paso, TX 79968, USA.

Funding

UTEP Border Biomedical Research CenterU54MD007592 · NIMHD · UNIVERSITY OF TEXAS EL PASO · PI Gabriel Andrew Frietze · 2019 to 2026
$35.1M
NIH HHS 3U54MD007592-27S1NIMHD NIH HHS U54 MD007592
6 · The paper itself

Abstract

COVID-19, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), remains an ongoing global health challenge. This study analyzed 3641 SARS-CoV-2 positive samples from the El Paso, Texas, community and hospitalized patients over 48 weeks from Fall 2021 to Summer 2022. The binational community along the U.S. southern border was predominantly SARS-CoV-2 Delta variant (B.1.617.2) positive for a 5-week period from September 2021 to January 2022 and quickly transitioned to the Omicron variant (B.1.1.529), which was first detected at the end of December 2021. Omicron replaced Delta as the predominant detectable variant in the community and was associated with a sharp increase in COVID-19 positivity rate, related hospitalizations, and newly reported cases. In this study, Omicron BA.1, BA.4, and BA.5 variants were overwhelmingly associated with S-gene dropout by qRT-PCR analysis unlike the Delta and Omicron BA.2 variants. The study reveals that a dominant variant, like Delta, can be rapidly replaced by a more transmissible variant, like Omicron, within a dynamic metropolitan border city, necessitating enhanced monitoring, readiness, and response from public health officials and healthcare workers.

Indexed as

COVID-19SARS-CoV-2Health PersonnelHospitalizationHumansCOVID-19Deltagenomic surveillancenext-generation sequencing (NGS)OmicronSARS-CoV-2

Identifiers

PMID36992367
PMCPMC10057517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.