Evidence map›Paper›PMID 36992350›Full record

ArticleViruses2023

Repurposing

Chia-Yin Lee, Anh Thuc Nguyen, Ly Hien Doan, Li-Wei Chu, Chih-Hung Chang, Hui-Kang Liu, I-Lin Lee, Teng-Hsu Wang, Jin-Mei Lai, Shih-Ming Tsao and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Chia-Yin LeeTaiwan National Graduate Program in Molecular Medicine, National Yang Ming Chiao Tung University and Academia Sinica, Taipei 112304, Taiwan.ORCID 0000-0002-5236-4231
Anh Thuc NguyenTaiwan National Graduate Program in Molecular Medicine, National Yang Ming Chiao Tung University and Academia Sinica, Taipei 112304, Taiwan.
Ly Hien DoanInstitute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0002-4557-1988
Li-Wei ChuDepartment and Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0002-6291-4436
Chih-Hung ChangDepartment of Orthopedic Surgery, Far Eastern Memorial Hospital, New Taipei City 220216, Taiwan.
Hui-Kang LiuDivision of Basic Chinese Medicine, National Research Institute of Chinese Medicine (NRICM), Ministry of Health and Welfare, Taipei 112304, Taiwan.ORCID 0000-0002-5297-6836
I-Lin LeePhytoHeath Corporation, Taipei 105403, Taiwan.
Teng-Hsu WangPhytoHeath Corporation, Taipei 105403, Taiwan.
Jin-Mei LaiDepartment of Life Science, College of Science and Engineering, Fu Jen Catholic University, New Taipei City 242062, Taiwan.
Shih-Ming TsaoDivision of Pulmonary Medicine, School of Medicine, Chung Shan Medical University Hospital, Chung Shan Medical University, Taichung 402306, Taiwan.
Hsiu-Jung LiaoDepartment of Medical Research, Far Eastern Memorial Hospital, New Taipei City 220216, Taiwan.
Yueh-Hsin PingDepartment and Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0003-2604-9913
Chi-Ying F HuangInstitute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
National Yang Ming Chiao Tung University · TWFar Eastern Memorial Hospital · TWChung Shan Medical University Hospital · TWFu Jen Catholic University · TWNational Research Institute of Chinese Medicine · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a serious threat to global public health. In an effort to develop novel anti-coronavirus therapeutics and achieve prophylactics, we used gene set enrichment analysis (GSEA) for drug screening and identified that

Indexed as

Angiotensin-Converting Enzyme 2COVID-19PolysaccharidesSpike Glycoprotein, CoronavirusAnti-Inflammatory AgentsAstragalus propinquusDrug RepositioningHumansMicroRNAsSARS-CoV-2Angiotensin-Converting Enzyme 2Anti-Inflammatory AgentsMicroRNAsPolysaccharidesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2COVID-19cytokine stormmacrophagesmicroRNAsviral entry

Identifiers

PMID36992350
PMCPMC10054482
OpenAlexW4322629155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.