Evidence map›Paper›PMID 36992312›Full record

ArticleViruses2023

Administration of Bacteriophages via Nebulization during Mechanical Ventilation: In Vitro Study and Lung Deposition in Macaques.

Sandrine Le Guellec, Jeoffrey Pardessus, Elsa Bodier-Montagutelli, Guillaume L'Hostis, Emilie Dalloneau, Damien Piel, Hakim Chouky Samaï, Antoine Guillon, Elvir Mujic, Emmanuelle Guillot-Combe and 6 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Sandrine Le GuellecDTF Aerodrug, Faculté de Médecine, Bâtiment M, 10 Boulevard Tonnellé, F-37032 Tours, France.
Jeoffrey PardessusINSERM, Centre d'Etude des Pathologies Respiratoires, CEPR U1100, Faculté de Médecine, 10 Boulevard Tonnellé, F-37032 Tours, France.ORCID 0000-0001-9861-2774
Elsa Bodier-MontagutelliINSERM, Centre d'Etude des Pathologies Respiratoires, CEPR U1100, Faculté de Médecine, 10 Boulevard Tonnellé, F-37032 Tours, France.
Guillaume L'HostisPherecydes Pharma, 22 Boulevard Benoni Goullin, F-44200 Nantes, France.ORCID 0000-0002-4337-610X
Emilie DalloneauCynbiose Respiratory, Site MAME, F-37000 Tours, France.
Damien PielPherecydes Pharma, 22 Boulevard Benoni Goullin, F-44200 Nantes, France.
Hakim Chouky SamaïPherecydes Pharma, 22 Boulevard Benoni Goullin, F-44200 Nantes, France.
Antoine GuillonINSERM, Centre d'Etude des Pathologies Respiratoires, CEPR U1100, Faculté de Médecine, 10 Boulevard Tonnellé, F-37032 Tours, France.
Elvir MujicDTFmedical, 19 rue de la Presse, F-42003 Saint Etienne, France.
Emmanuelle Guillot-CombeDirection Générale de l'Armement, Agence de l'Innovation de Défense AID Biologie et Biotechnologies, 60 Boulevard Martial Valin, F-75509 Paris, France.
Stephan EhrmannINSERM, Centre d'Etude des Pathologies Respiratoires, CEPR U1100, Faculté de Médecine, 10 Boulevard Tonnellé, F-37032 Tours, France.ORCID 0000-0001-6221-4467
Eric MorelloFaculté de Médecine, Université de Tours, 10 Boulevard Tonnellé, F-37032 Tours, France.
Jérôme GabardPherecydes Pharma, 22 Boulevard Benoni Goullin, F-44200 Nantes, France.
Nathalie Heuzé-Vourc'hINSERM, Centre d'Etude des Pathologies Respiratoires, CEPR U1100, Faculté de Médecine, 10 Boulevard Tonnellé, F-37032 Tours, France.ORCID 0000-0003-4929-5068
Cindy FevrePherecydes Pharma, 22 Boulevard Benoni Goullin, F-44200 Nantes, France.
Laurent VecellioDTF Aerodrug, Faculté de Médecine, Bâtiment M, 10 Boulevard Tonnellé, F-37032 Tours, France.
Université de Tours · FRAgence de l'innovation de défense

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriophages have been identified as a potential treatment option to treat lung infection in the context of antibiotic resistance. We performed a preclinical study to predict the efficacy of delivery of bacteriophages against

Indexed as

BacteriophagesPodoviridaeAerosolsAnimalsLungMacacaMyoviridaeNebulizers and VaporizersRespiration, ArtificialAerosolsbacteriophagesin vitro viabilityin vivo aerosol depositionlung deposition predictionmechanical ventilationmorphotypenebulization

Identifiers

PMID36992312
PMCPMC10051375
OpenAlexW4321496257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.