Evidence map›Paper›PMID 36992287›Full record

ArticleVaccines2023

Adherence to Vaccines in Adult Patients with Immune-Mediated Inflammatory Diseases: A Two-Year Prospective Portuguese Cohort Study.

Candida Abreu, Antonio Martins, Fernando Silva, Gabriela Canelas, Lucia Ribeiro, Stefano Pinto, Antonio Sarmento, Fernando Magro

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Candida AbreuDepartment of Infectious Diseases, São João Hospital Center, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.ORCID 0000-0001-6464-7063
Antonio MartinsDepartment of Infectious Diseases, São João Hospital Center, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.
Fernando SilvaDepartment of Infectious Diseases, São João Hospital Center, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.
Gabriela CanelasDepartment of Infectious Diseases, São João Hospital Center, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.
Lucia RibeiroDepartment of Infectious Diseases, São João Hospital Center, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.
Stefano PintoDepartment of Infectious Diseases, São João Hospital Center, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.
Antonio SarmentoDepartment of Infectious Diseases, São João Hospital Center, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.
Fernando MagroUnit of Pharmacology and Therapeutics, Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.ORCID 0000-0003-2634-9668
Universidade do Porto · PTNational Institute of Engineering, Technology and Innovation · PT

Funding

Pfizer Portugal 42420671.
6 · The paper itself

Abstract

backgroundPatients with immune-mediated inflammatory diseases (IMIDs) treated with immunomodulatory therapy present an increased susceptibility to infections. Vaccination is a crucial element in the management of IMID patients; however, rates remain suboptimal. This study intended to clarify the adherence to prescribed vaccines. MATERIALS AND

methodsThis prospective cohort study included 262 consecutive adults with inflammatory bowel disease and rheumatological diseases who underwent an infectious diseases evaluation before initiating or switching immunosuppressive/biological therapy. Vaccine prescription and adherence were assessed during an infectious diseases (ID) consultation using a real-world multidisciplinary clinical project.

resultsAt baseline, less than 5% had all their vaccines up-to-date. More than 650 vaccines were prescribed to 250 (95.4%) patients. The most prescribed were pneumococcal and influenza vaccines, followed by hepatitis A and B vaccines. Adherence to each of the vaccines ranged from 69.1-87.3%. Complete adherence to vaccines occurred in 151 (60.4%) patients, while 190 (76%) got at least two-thirds of them. Twenty patients (8%) did not adhere to any of the vaccines. No significant differences were found in the adherence rates of patients with different sociodemographic and health-related determinants.

conclusionsID physicians can play a role in the process of increasing vaccine prescription and adherence. However, more data on patients' beliefs and vaccine hesitancy, along with mobilization of all health care professionals and adequate local interventions, shall be considered to improve vaccine adherence.

Indexed as

immunosuppressed patientsinflammatory bowel diseasesrheumatological diseasesvaccine adherencevaccine prescription

Identifiers

PMID36992287
PMCPMC10056318
OpenAlexW4327950126

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.