Evidence map›Paper›PMID 36992210›Full record

ArticleVaccines2023

Predictors of Recurrent Laboratory-Confirmed Symptomatic SARS-CoV-2 Infections in a Cohort of Healthcare Workers.

Xóchitl Trujillo, Oliver Mendoza-Cano, Mónica Ríos-Silva, Miguel Huerta, José Guzmán-Esquivel, Verónica Benites-Godínez, Agustin Lugo-Radillo, Jaime Alberto Bricio-Barrios, Martha I Cárdenas-Rojas, Eder Fernando Ríos-Bracamontes and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xóchitl TrujilloCentro Universitario de Investigaciones Biomédicas, Universidad de Colima, Av. 25 de Julio 965, Col. Villas San Sebastián, Colima 28045, Mexico.ORCID 0000-0001-8146-5667
Oliver Mendoza-CanoFacultad de Ingeniería Civil, Universidad de Colima, km. 9 Carretera Colima-Coquimatlán, Coquimatlán 28400, Mexico.ORCID 0000-0001-9614-4946
Mónica Ríos-SilvaCentro Universitario de Investigaciones Biomédicas, CONACyT-Universidad de Colima, Av. 25 de Julio 965, Col. Villas San Sebastián, Colima 28045, Mexico.ORCID 0000-0002-2883-4619
Miguel HuertaCentro Universitario de Investigaciones Biomédicas, Universidad de Colima, Av. 25 de Julio 965, Col. Villas San Sebastián, Colima 28045, Mexico.ORCID 0000-0001-8515-0777
José Guzmán-EsquivelUnidad de Investigación en Epidemiología Clínica, Instituto Mexicano del Seguro Social, Av. Lapislázuli 250, Col. El Haya, Villa de Álvarez 28984, Mexico.ORCID 0000-0002-6727-0051
Verónica Benites-GodínezCoordinación de Educación en Salud, Instituto Mexicano del Seguro Social, Calzada del Ejercito Nacional 14, Col. Fray Junípero Serra, Tepic 63160, Mexico.
Agustin Lugo-RadilloCONACyT-Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Ex Hacienda Aguilera S/N, Carr. a San Felipe del Agua, Oaxaca 68020, Mexico.ORCID 0000-0001-6689-2783
Jaime Alberto Bricio-BarriosFacultad de Medicina, Universidad de Colima, Av. Universidad 333, Col. Las Víboras, Colima 28040, Mexico.ORCID 0000-0001-5667-5179
Martha I Cárdenas-RojasUnidad de Investigación en Epidemiología Clínica, Instituto Mexicano del Seguro Social, Av. Lapislázuli 250, Col. El Haya, Villa de Álvarez 28984, Mexico.
Eder Fernando Ríos-BracamontesDepartamento de Medicina Interna, Hospital General de Zona No. 1, Instituto Mexicano del Seguro Social, Av. Lapislázuli 250, Col. El Haya, Villa de Álvarez 28984, Mexico.
Vannya Marisol Ortega-MacíasFacultad de Medicina, Universidad de Colima, Av. Universidad 333, Col. Las Víboras, Colima 28040, Mexico.
Valeria Ruiz-Montes de OcaEscuela de Medicina, Plantel Guadalajara, Universidad Cuauhtémoc, Av. del Bajío No. 5901, Col. Del Bajío, Zapopan 45019, Mexico.
Efrén Murillo-ZamoraUnidad de Investigación en Epidemiología Clínica, Instituto Mexicano del Seguro Social, Av. Lapislázuli 250, Col. El Haya, Villa de Álvarez 28984, Mexico.ORCID 0000-0002-1118-498X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRepeated SARS-CoV-2 infections are plausible and related published data are scarce. We aimed to identify factors associated with the risk of recurrent (three episodes) laboratory-confirmed symptomatic SARS-CoV-2 infections.

methodsA retrospective cohort study was conducted, and 1,700 healthcare workers were enrolled. We used risk ratios (RR) and 95% confidence intervals (CI) to evaluate the factors associated with symptomatic SARS-CoV-2 infections.

resultsWe identified 14 participants with recurrent illness episodes. Therefore, the incidence rate was 8.5 per 10,000 person months. In a multiple-model study, vaccinated adults (vs. unvaccinated, RR = 1.05 [1.03-1.06]) and those with a severe first illness episode (vs. mild disease, RR = 1.05 [1.01-1.10]) were at increased risk for repeated symptomatic SARS-CoV-2 reinfections. Increasing age showed a protective effect (per each additional year of age: RR = 0.98 [0.97-0.99]).

conclusionsOur results suggest that recurrent SARS-CoV-2 infections are rare events in adults, and they seem to be determined, partially, by vaccination status and age.

Indexed as

COVID-19reinfectionSARS-CoV-2

Identifiers

PMID36992210
PMCPMC10054101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.