Evidence map›Paper›PMID 36992167›Full record

ArticleVaccines2023

Zika Vaccine Microparticles (MPs)-Loaded Dissolving Microneedles (MNs) Elicit a Significant Immune Response in a Pre-Clinical Murine Model.

Akanksha Kale, Devyani Joshi, Ipshita Menon, Priyal Bagwe, Smital Patil, Sharon Vijayanand, Keegan Braz Gomes, Mohammad N Uddin, Martin J D'Souza

Abstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akanksha KaleVaccine Nanotechnology Laboratory, Center for Drug Delivery and Research, Mercer University College of Pharmacy, Atlanta, GA 30341, USA.ORCID 0000-0003-2314-3867
Devyani JoshiVaccine Nanotechnology Laboratory, Center for Drug Delivery and Research, Mercer University College of Pharmacy, Atlanta, GA 30341, USA.
Ipshita MenonVaccine Nanotechnology Laboratory, Center for Drug Delivery and Research, Mercer University College of Pharmacy, Atlanta, GA 30341, USA.ORCID 0000-0003-2686-8070
Priyal BagweVaccine Nanotechnology Laboratory, Center for Drug Delivery and Research, Mercer University College of Pharmacy, Atlanta, GA 30341, USA.ORCID 0000-0001-7151-5018
Smital PatilVaccine Nanotechnology Laboratory, Center for Drug Delivery and Research, Mercer University College of Pharmacy, Atlanta, GA 30341, USA.
Sharon VijayanandVaccine Nanotechnology Laboratory, Center for Drug Delivery and Research, Mercer University College of Pharmacy, Atlanta, GA 30341, USA.ORCID 0000-0002-4365-4157
Keegan Braz GomesVaccine Nanotechnology Laboratory, Center for Drug Delivery and Research, Mercer University College of Pharmacy, Atlanta, GA 30341, USA.
Mohammad N UddinVaccine Nanotechnology Laboratory, Center for Drug Delivery and Research, Mercer University College of Pharmacy, Atlanta, GA 30341, USA.
Martin J D'SouzaVaccine Nanotechnology Laboratory, Center for Drug Delivery and Research, Mercer University College of Pharmacy, Atlanta, GA 30341, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the global Zika epidemic in 2015-16 fueled vaccine development efforts, there is no approved Zika vaccine or treatment available to date. Current vaccine platforms in clinical trials are administered via either subcutaneous or intramuscular injections, which are painful and decrease compliance. Therefore, in the present study, we explored Zika vaccine microparticles (MPs)-loaded dissolving microneedles (MNs) with adjuvant MPs encapsulating Alhydrogel

Indexed as

microneedlesmicroparticlesvaccineZika

Identifiers

PMID36992167
PMCPMC10056879

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.