Evidence map›Paper›PMID 36992089›Full record

ArticleVaccines2023

Adverse Events to Comirnaty Vaccine Are Linked to Sex, Age and BMI: Should We Consider Reducing the Dose for Females?

Elena Azzolini, Maximiliano Mollura, Chiara Pozzi, Leonardo Ubaldi, Alberto Mantovani, Carlo Selmi, Riccardo Barbieri, Maria Rescigno

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elena AzzoliniIRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, MI, Italy.
Maximiliano MolluraPolitecnico di Milano, Department of Electronic, Information and Bioengineering, Piazza Leonardo da Vinci 32, 20133 Milano, MI, Italy.ORCID 0000-0002-2248-8145
Chiara PozziIRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, MI, Italy.ORCID 0000-0003-2153-6130
Leonardo UbaldiDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, MI, Italy.
Alberto MantovaniIRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, MI, Italy.
Carlo SelmiIRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, MI, Italy.ORCID 0000-0002-0323-0376
Riccardo BarbieriPolitecnico di Milano, Department of Electronic, Information and Bioengineering, Piazza Leonardo da Vinci 32, 20133 Milano, MI, Italy.ORCID 0000-0001-9381-3833
Maria RescignoIRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, MI, Italy.ORCID 0000-0002-6464-509X

Funding

Ministero della Salute Ricerca Corrente
6 · The paper itself

Abstract

An important issue that is often neglected is the difference between male and female genders in response to medical treatments. In the context of COVID-19 vaccine administration, despite identical protocol strategies, it has been observed that females often suffer more adverse consequences than males. Here, we analyzed the adverse events (AEs) of the Comirnaty vaccine in a population of 2385 healthcare workers as a function of age, sex, COVID-19 history and BMI. Using logistic regression analysis, we showed that these variables may contribute to the development of AEs, particularly in young subjects, females and individuals with a BMI below 25 kg/m

Indexed as

adverse eventsCOVID-19vaccine

Identifiers

PMID36992089
PMCPMC10055873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.