Evidence map›Paper›PMID 36992077›Full record

ArticleVaccines2023

Clinical and Serological Follow-Up of 216 Patients with Hematological Malignancies after Vaccination with Pfizer-BioNT162b2 mRNA COVID-19 in a Real-World Study.

Jean-François Rossi, Emmanuel Bonnet, Christel Castelli, Marion Velensek, Emma Wisniewski, Sophie Heraud, Rania Boustany, Céleste David, Jérôme Dinet, Roland Sicard and 4 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Jean-François RossiInstitut du Cancer Avignon-Provence, Sainte Catherine, 84000 Avignon, France.
Emmanuel BonnetRecherche Clinique Clinique Beau Soleil-Nouvelles Technologies, 34070 Montpellier, France.
Christel CastelliRecherche Clinique Clinique Beau Soleil-Nouvelles Technologies, 34070 Montpellier, France.
Marion VelensekInstitut du Cancer Avignon-Provence, Sainte Catherine, 84000 Avignon, France.
Emma WisniewskiInstitut du Cancer Avignon-Provence, Sainte Catherine, 84000 Avignon, France.
Sophie HeraudInstitut du Cancer Avignon-Provence, Sainte Catherine, 84000 Avignon, France.
Rania BoustanyInstitut du Cancer Avignon-Provence, Sainte Catherine, 84000 Avignon, France.
Céleste DavidInstitut du Cancer Avignon-Provence, Sainte Catherine, 84000 Avignon, France.
Jérôme DinetThess Corporate Inc., 34070 Montpellier, France.
Roland SicardInstitut du Cancer Avignon-Provence, Sainte Catherine, 84000 Avignon, France.
Jean-Pierre DauresRecherche Clinique Clinique Beau Soleil-Nouvelles Technologies, 34070 Montpellier, France.
Marion BonifacyBioaxiome-Inovie, 84000 Avignon, France.
Lysiane MoussetBioaxiome-Inovie, 84000 Avignon, France.
Emmanuel GoffartBioaxiome-Inovie, 84000 Avignon, France.
Institut Sainte Catherine · FRClinique du Millénaire · FRUniversité de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematological malignancies (HMs) have heterogeneous serological responses after vaccination due to disease or treatment. The aim of this real-world study was to analyze it after Pfizer-BioNT162b2 mRNA vaccination in 216 patients followed up for 1 year. The first 43 patients had an initial follow-up by a telemedicine (TM) system with no major events reported. The anti-spike IgG antibodies were checked 3-4 weeks post-first vaccination and every 3-4 months, by two standard bioassays and a rapid serological test (RST). Vaccine boosts were given when the level was <7 BAU/mL. Patients who did not seroconvert after 3-4 doses received tixagevimab/cilgavimab (TC). Fifteen results were discordant between two standard bioassays. Good agreement was observed between the standard and RST in 97 samples. After two doses, 68% were seroconverted (median = 59 BAU/mL) with a median of 162 BAU/mL and 9 BAU/mL, respectively, in untreated and treated patients (

Indexed as

COVID-19hematological malignanciesserological follow-up

Identifiers

PMID36992077
PMCPMC10057553
OpenAlexW4321457603

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.