Evidence map›Paper›PMID 36991740›Full record

ArticleSensors (Basel, Switzerland)2023

Serotonin-Derived Fluorophore: A Novel Fluorescent Biomaterial for Copper Detection in Urine.

Mariagrazia Lettieri, Simona Scarano, Laura Caponi, Andrea Bertolini, Alessandro Saba, Pasquale Palladino, Maria Minunni

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mariagrazia LettieriDepartment of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.ORCID 0000-0001-6945-7576
Simona ScaranoDepartment of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.ORCID 0000-0002-8050-1715
Laura CaponiLaboratory of Clinical Pathology, University Hospital of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-9597-9749
Andrea BertoliniDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-4810-7061
Alessandro SabaLaboratory of Clinical Pathology, University Hospital of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-0611-5549
Pasquale PalladinoDepartment of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.ORCID 0000-0002-3869-5085
Maria MinunniDepartment of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.ORCID 0000-0003-0906-0862
University of Florence · ITUniversity of Pisa · ITAzienda Ospedaliera Universitaria Pisana · IT

Funding

Ministry of University and Research (MUR) Dipartimenti di Eccellenza
6 · The paper itself

Abstract

We took advantage of the fluorescent features of a serotonin-derived fluorophore to develop a simple and low-cost assay for copper in urine. The quenching-based fluorescence assay linearly responds within the concentration range of clinical interest in buffer and in artificial urine, showing very good reproducibility (CV

Indexed as

CopperSerotoninFluorescent DyesHumansLimit of DetectionMass SpectrometryReproducibility of ResultsSpectrometry, FluorescenceCopperFluorescent DyesSerotonincopper-dependent diseasescopper detectioncopper poisoningfluorescence quenchingserotoninserotonin-derived fluorophoreurine analysis

Identifiers

PMID36991740
PMCPMC10055690
OpenAlexW4324092313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.