ArticleJournal of bronchology & interventional pulmonology2024
Diagnostic Value of Transbronchial Lung Cryobiopsy Using an Ultrathin Cryoprobe and Guide Sheath for Peripheral Pulmonary Lesions.
Article in Journal of bronchology & interventional pulmonology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
- Comparative study of transbronchial cryobiopsy and transbronchial biopsy for diagnostic yield in peripheral pulmonary lesions.Annals of medicine · 2026Article
- Minimally Invasive Sampling Techniques for Pancreatic and Pulmonary Nodules: A Review of the Evolution of Guidance and Sampling Methods.Diagnostic cytopathology · 2026Review
- Comparison of diagnostic yield between electromagnetic navigation bronchoscopy-guided forceps biopsy and target-fixing technique-assisted RP-EBUS-guided transbronchial cryobiopsy with a guide sheath for peripheral lung lesions.Translational lung cancer research · 2026Article
- Diagnostic Yield and Safety of Radial Probe Endobronchial Ultrasound-Guided Transbronchial Lung Cryobiopsy with a Guide Sheath in Pulmonary Lesions < 3 cm.Diagnostics (Basel, Switzerland) · 2026Article
- Diagnostic accuracy and safety of 1.1-mm cryoprobe biopsy for peripheral pulmonary lesions with or without oversheath.Translational lung cancer research · 2026Article
- Innovations in Robotic-Assisted Bronchoscopy: Current Trends and Future Prospects.Diagnostics (Basel, Switzerland) · 2026Review
- Transbronchial cryobiopsy for peripheral pulmonary lesions using ultrathin bronchoscopy: a narrative review.Journal of thoracic disease · 2026Review
- Transbronchial cryobiopsy for diagnosing pulmonary hyalinizing granuloma: a case report.BMC pulmonary medicine · 2025Article
- Flexible Bronchoscopic En Bloc Cryoextraction of Endobronchial Leiomyoma Using a 1.7-mm Cryoprobe: A Case Report with One-Year Follow-Up.Diagnostics (Basel, Switzerland) · 2025Article
- Outcomes of radial probe endobronchial ultrasound-guided transbronchial lung cryobiopsy using guide sheath and the target fixing technique.Translational lung cancer research · 2025Article
- Complete resolution of non-tuberculous mycobacterial pulmonary nodule following cryobiopsy: The first case report.Diagnostic pathology · 2025Article
- Tumor microscopically-absent on resection specimen after Bronchoscopic Cryobiopsy: TuMORS-ABC.Respiratory medicine case reports · 2025Article
- Diagnosis of leukemic lung infiltration mimicking fungal infection by transbronchial lung cryobiopsy: the first case report.BMC pulmonary medicine · 2024Article
- Advanced Bronchoscopic Diagnostic Techniques in Lung Cancer.Tuberculosis and respiratory diseases · 2024Article
- Exploring the optimal freeze time and passes of the ultrathin cryoprobe in transbronchial cryobiopsy of peripheral pulmonary lesions.ERJ open research · 2024Article
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe addition of cryobiopsy to conventional biopsy methods improves the diagnostic yield of peripheral pulmonary lesions. Moreover, cryobiopsy with a guide sheath (GS) provides additional diagnostic benefits. Semi-real-time biopsy can be repeatedly performed using conventional biopsy devices and a GS, and subsequent cryobiopsy can be easily performed at the same location. Recently, a disposable 1.1 mm-diameter ultrathin cryoprobe has been developed and can be used with a 1.95 mm GS in a 2.0 mm working channel. In this study, we evaluated the diagnostic performance of transbronchial lung cryobiopsy (TBLC) with the 1.1 mm cryoprobe and a GS in patients with peripheral pulmonary lesions.
methodsWe retrospectively reviewed the medical records of patients who underwent endobronchial ultrasound transbronchial lung biopsy with a guide sheath and TBLC from July 23, 2021 to April 30, 2022 at Chungnam National University Hospital.
resultsOf a consecutive series of 229 patients, 199 were included. The diagnostic yields of forceps biopsy and cryobiopsy were 65.3% (130/199) and 84.4% (168/199), respectively, and the total diagnostic yield was 91.5% (182/199) ( P <0.001 vs. forceps biopsy). Multivariate analysis showed that solid lesion morphology [adjusted odds ratio (OR) 3.659, P =0.002] was associated with a significantly greater diagnostic yield of cryobiopsy, whereas a lesion diameter >20 mm ( P =0.026; adjusted OR 3.816) and 'within' orientation ( P =0.004; adjusted OR 6.174) were associated with a significantly greater overall diagnostic yield.
conclusionTBLC using an ultrathin cryoprobe and GS markedly improves the diagnostic yield.
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