Evidence map›Paper›PMID 36991490›Full record

ArticleTrials2023

A structured, telephone-delivered intervention to reduce methamphetamine use: study protocol for a parallel-group randomised controlled trial.

Dan I Lubman, Victoria Manning, Shalini Arunogiri, Kate Hall, John Reynolds, Peta Stragalinos, Rachel Petukhova, Robyn Gerhard, Jonathan Tyler, Anna Bough and 2 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04713124 (Ready2Change-Methamphetmine), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04713124 nacompletednot on this map

Ready2Change-Methamphetmine (R2C-M): A Randomised Controlled Trial of a Telephone-delivered Intervention to Reduce Methamphetamine Use

TypeinterventionalSponsorTurning PointRan2021 to 2024Enrolled204ConditionsMethamphetamine Use DisorderArmsR2C-M, Self-help booklet
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dan I LubmanTurning Point, Eastern Health, Melbourne, Victoria, Australia. dan.lubman@monash.edu.
Victoria ManningTurning Point, Eastern Health, Melbourne, Victoria, Australia.
Shalini ArunogiriTurning Point, Eastern Health, Melbourne, Victoria, Australia.
Kate HallSchool of Psychology, Deakin University, Geelong, Victoria, Australia.
John ReynoldsFaculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.
Peta StragalinosTurning Point, Eastern Health, Melbourne, Victoria, Australia.
Rachel PetukhovaTurning Point, Eastern Health, Melbourne, Victoria, Australia.
Robyn GerhardTurning Point, Eastern Health, Melbourne, Victoria, Australia.
Jonathan TylerTurning Point, Eastern Health, Melbourne, Victoria, Australia.
Anna BoughTurning Point, Eastern Health, Melbourne, Victoria, Australia.
Anthony HarrisCentre for Health Economics, Monash University, Melbourne, Victoria, Australia.
Jasmin GriggTurning Point, Eastern Health, Melbourne, Victoria, Australia.

Funding

National Health and Medical Research Council APP1186268
6 · The paper itself

Abstract

backgroundAustralia has one of the highest rates of methamphetamine (MA) use in the world; however, uptake of in-person psychological treatment remains extremely low due to numerous individual (e.g. stigma, shame) and structural (e.g. service accessibility, geographical location) barriers to accessing care. Telephone-delivered interventions are ideally placed to overcome many of the known barriers to treatment access and delivery. This randomised controlled trial (RCT) will examine the efficacy of a standalone, structured telephone-delivered intervention to reduce MA problem severity and related harms.

methodsThis study is a double-blind, parallel-group RCT. We will recruit 196 ± 8 individuals with mild to moderate MA use disorder from across Australia. After eligibility and baseline assessments, participants will be randomly allocated to receive either the Ready2Change-Methamphetamine (R2C-M) intervention (n = 98 ± 4; four to six telephone-delivered intervention sessions, R2C-M workbooks and MA information booklet) or control (n = 98 ± 4; four to six ≤5-min telephone check-ins and MA information booklet including information on accessing further support). Telephone follow-up assessments will occur at 6 weeks and 3, 6 and 12 months post-randomisation. The primary outcome is change in MA problem severity (Drug Use Disorders Identification Test, DUDIT) at 3 months post-randomisation. Secondary outcomes are as follows: MA problem severity (DUDIT) at 6 and 12 months post-randomisation, amount of methamphetamine used, methamphetamine use days, methamphetamine use disorder criteria met, cravings, psychological functioning, psychotic-like experiences, quality of life and other drug use days (at some or all timepoints of 6 weeks and 3, 6 and 12 months post-randomisation). Mixed-methods program evaluation will be performed and cost-effectiveness will be examined. DISCUSSION: This study will be the first RCT internationally to assess the efficacy of a telephone-delivered intervention for MA use disorder and related harms. The proposed intervention is expected to provide an effective, low-cost, scalable treatment for individuals otherwise unlikely to seek care, preventing future harms and reducing health service and community costs.

trial registrationClinicalTrials.gov NCT04713124 . Pre-registered on 19 January 2021.

Indexed as

TelephoneAustraliaCost-Benefit AnalysisDouble-Blind MethodHumansRandomized Controlled Trials as TopicTreatment OutcomeMethamphetaminePsychological interventionRandomised controlled trialSubstance use disorderTelehealthTreatment

Identifiers

PMID36991490
PMCPMC10052286

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.