Evidence map›Paper›PMID 36991176›Full record

ArticleNeurocritical care2024

Heart Rate Variability in Patients with Spontaneous Intracerebral Hemorrhage and its Relationship with Clinical Outcomes.

Yang Qu, Yi Yang, Xin Sun, Hong-Yin Ma, Peng Zhang, Reziya Abuduxukuer, Hong-Jing Zhu, Jia Liu, Pan-Deng Zhang, Zhen-Ni Guo

Abstract read
PubMed Publisher
In one paragraph

Article in Neurocritical care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. The Roles of Heart Rate Variability in Cerebral Stroke.Neuropsychiatric disease and treatment · 2025
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yang QuStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Yi YangStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Xin SunStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Hong-Yin MaStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Peng ZhangStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Reziya AbuduxukuerStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Hong-Jing ZhuStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Jia LiuShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Pan-Deng ZhangShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Zhen-Ni GuoStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China. zhen1ni2@jlu.edu.cn.
First Hospital of Jilin University · CNJilin University · CNShenzhen Institutes of Advanced Technology · CN

Funding

Natural Science Foundation of China 81901192Norman Bethune Program of Jilin University 2022B02the Jilin Provincial Key Laboratory 20190901005JCthe Science and technology department of Jilin province 20180623052TC
6 · The paper itself

Abstract

backgroundAlthough abnormal heart rate variability (HRV) is frequently observed in patients with spontaneous intracerebral hemorrhage (ICH), its time course and presentation of different indices remain unclear, and few studies have focused on its association with clinical outcomes.

methodsWe prospectively recruited consecutive patients with spontaneous ICH between June 2014 and June 2021. HRV was evaluated twice during hospitalization (within 7 days and 10-14 days after stroke). Time and frequency domain indices were calculated. A modified Rankin Scale score ≥ 3 at 3 months was defined as a poor outcome.

resultsFinally, 122 patients with ICH and 122 age- and sex-matched volunteers were included. Compared with controls, time domain and absolute frequency domain HRV parameters (total power, low frequency [LF], and high frequency [HF]) in the ICH group were significantly decreased within 7 days and 10-14 days. For relative values, normalized LF (LF%) and LF/HF were significantly higher, whereas normalized HF (HF%) was significantly lower, in the patient group than in the control group. Furthermore, LF% and HF% measured at 10-14 days were independently associated with 3-month outcomes.

conclusionsHRV values were impaired significantly within 14 days after ICH. Furthermore, HRV indices measured 10-14 days after ICH were independently associated with 3-month outcomes.

Indexed as

Cerebral HemorrhageStrokeArrhythmias, CardiacHeart RateHospitalizationHumansAutonomic dysfunctionBeat-to-beatHeart rate variabilityIntracerebral hemorrhageOutcomes

Identifiers

PMID36991176
OpenAlexW4361294472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.