ArticleNature communications2023
White matter disconnection of left multiple demand network is associated with post-lesion deficits in cognitive control.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Structural brain correlates in major depressive disorder, anxiety disorders, and post-traumatic stress disorder: a diffusion tensor imaging meta-analysis.Psychological medicine · 2025Pooled it
- A clinical neuroimaging platform for rapid, automated lesion detection and personalized post-stroke outcome prediction.NPJ digital medicine · 2026Article
- Integrating individualized connectome with amyloid pathology improves predictive modeling of future cognitive decline.Communications medicine · 2025Article
- Limitations of Correlation Coefficients in Research on Functional Connectomes and Psychological Processes.Human brain mapping · 2025Review
- The inferior fronto-occipital fasciculus: bridging phylogeny, ontogeny and functional anatomy.Brain : a journal of neurology · 2025Review
- Susceptibility to multitasking in stroke is associated to multiple-demand system damage and leads to lateralized visuospatial deficits.Communications biology · 2025Article
- Resting-state connectivity and task-based cortical response in post-stroke executive dysfunction: A fNIRS study.Neuroimage. Reports · 2025Article
- Reward Decision Network Disconnection in Poststroke Apathy: A Prospective Multimodality Imaging Study.Human brain mapping · 2025Article
- Cognitive control & the anterior cingulate cortex: Necessity & coherence.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Enhancing cognitive performance prediction by white matter hyperintensity connectivity assessment.Brain : a journal of neurology · 2024Article
- Article
- Computational limits to the legibility of the imaged human brain.NeuroImage · 2024Article
- Enhancing Cognitive Performance Prediction through White Matter Hyperintensity Connectivity Assessment: A Multicenter Lesion Network Mapping Analysis of 3,485 Memory Clinic Patients.medRxiv : the preprint server for health sciences · 2024Article
- White matter disconnection of left multiple demand network is associated with post-lesion deficits in cognitive control.Nature communications · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Cognitive control modulates other cognitive functions to achieve internal goals and is important for adaptive behavior. Cognitive control is enabled by the neural computations distributed over cortical and subcortical areas. However, due to technical challenges in recording neural activity from the white matter, little is known about the anatomy of white matter tracts that coordinate the distributed neural computations that support cognitive control. Here, we leverage a large sample of human patients with focal brain lesions (n = 643) and investigate how lesion location and connectivity profiles account for variance in cognitive control performance. We find that lesions in white matter connecting left frontoparietal regions of the multiple demand network reliably predict deficits in cognitive control performance. These findings advance our understanding of the white matter correlates of cognitive control and provide an approach for incorporating network disconnection to predict deficits following lesions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.