Evidence map›Paper›PMID 36990941›Full record

ArticleUrologic oncology2023

The effect of treatment on work productivity in patients with bladder cancer.

Lauren Ahlschlager, Sean McCabe, Allison M Deal, Amy Guo, Kathryn H Gessner, Robert Lipman, Stephanie Chisolm, John L Gore, Angela B Smith

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Urologic oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Lauren AhlschlagerDepartment of Urology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Sean McCabeIndiana School of Medicine, Indianapolis, IN.
Allison M DealIndiana School of Medicine, Indianapolis, IN.
Amy GuoFergene, Boston, MA.
Kathryn H GessnerDepartment of Urology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Robert LipmanBladder Cancer Advocacy Network, Bethesda, MD.
Stephanie ChisolmBladder Cancer Advocacy Network, Bethesda, MD.
John L GoreDepartment of Urology, University of Washington, Seattle, WA.
Angela B SmithDepartment of Urology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Indiana School of Medicine, Indianapolis, IN. Electronic address: angela_smith@med.unc.edu.
University of North Carolina at Chapel Hill · USBladder Cancer Advocacy Network · USIndiana University – Purdue University Indianapolis · USUniversity of Washington · US

Funding

UNC Integrated Translational Oncology Program (UNC-iTOP)T32CA244125 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WILLIAM Y. KIM, Jen Jen Yeh · 2019 to 2026
$3.9M
NCI NIH HHS T32 CA244125
6 · The paper itself

Abstract

objectiveTo describe the impact of bladder-preserving treatment vs. cystectomy on work productivity and activity impairment (WPAI) among patients with bladder cancer.

methodsUsing cross-sectional survey data, we constructed 2-part models involving both logistic and linear prediction to describe the relationship between WPAI and treatment modality among patients with non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC).

resultsA total of 848 patients were included in the analysis. Patients with NMIBC who had cystectomy were more likely to experience activity impairment compared with those receiving bladder-preserving treatment (OR: 4.25, 95% CI: 2.28-7.93). Among patients with MIBC, cystectomy was protective against increasing presenteeism (e^β: 0.41, 95% CI: 0.23-0.71) and productivity loss (e^β: 0.44, 95% CI: 0.21-0.88); however, the opposite effect was seen for absenteeism treatment (e^β: 4.82, 95% CI: 1.72-13.49).

conclusionCystectomy increased the odds of experiencing activity impairment for patients with NMIBC. However, for patients with MIBC, cystectomy appears to be protective for presenteeism and productivity loss. Further work is needed in order to better understand these important relationships and improve both patient counseling and shared decision-making.

Indexed as

Urinary Bladder NeoplasmsCross-Sectional StudiesCystectomyHumansNeoplasm InvasivenessBladder cancerBladder-sparing treatmentCystectomyPatient-reported outcomesUrinary bladder neoplasmsWork productivity

Identifiers

PMID36990941
PMCPMC10330641
OpenAlexW4360992688

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.