SynthesisNeurology2023
CT Perfusion vs Noncontrast CT for Late Window Stroke Thrombectomy: A Systematic Review and Meta-analysis.
Synthesis in Neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Selection by Noncontrast Computed Tomography With or Without Computed Tomography Angiography Versus Computed Tomography Perfusion for Endovascular Therapy in Patients With Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2025Pooled it
- Beyond conventional imaging: A systematic review and meta-analysis assessing the impact of computed tomography perfusion on ischemic stroke outcomes in the late window.International journal of stroke : official journal of the International Stroke Society · 2025Pooled it
- Impact of stroke imaging selection modality on endovascular thrombectomy outcomes in the early and extended time windows: A meta-analysis.Brain and behavior · 2024Pooled it
- Pooled it
- Review
- Simple against advanced imaging for the selection of stroke therapy in the extended window (VESTA study).European stroke journal · 2026Article
- Comparison of non-contrast CT, CT perfusion, and CT angiography for predicting delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.Insights into imaging · 2026Article
- Endovascular thrombectomy for acute ischemic stroke: evolving patient selection, procedural strategies, and adjunctive therapies.Frontiers in neurology · 2026Review
- Acute stroke imaging protocols and decision-making criteria for endovascular thrombectomy in acute ischemic stroke: a nationwide survey of thrombectomy-capable centers in Korea.BMC neurology · 2025Article
- Evaluating the Safety and Efficacy of Intravenous Thrombolysis in Acute Ischemic Stroke Patients Without Perfusion Deficit: A Retrospective Analysis.Brain sciences · 2025Article
- Tailored Treatment of Acute Ischemic Stroke: A Narrative Review of Evidence-Based Strategies by Imaging Type and Thrombectomy Availability.Medicina (Kaunas, Lithuania) · 2025Review
- Acute Infarct Core Volume Estimation on Noncontrast Computed Tomography With a Deep Learning Algorithm.Stroke (Hoboken, N.J.) · 2025Article
- Predictors of futile recanalization after endovascular therapy in anterior circulation stroke with large core infarction.Frontiers in neurology · 2025Article
- Improving acute stroke assessment in non-enhanced computed tomography: automated tool for early ischemic lesion volume detection.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Epidemiology, organization, diagnosis and treatment of acute ischemic stroke.European journal of radiology open · 2023Article
- Automated advanced imaging in acute ischemic stroke. Certainties and uncertainties.European journal of radiology open · 2023Article
- Endovascular Therapy for Acute Stroke: New Evidence and Indications.Journal of neuroendovascular therapy · 2023Review
- Sequential mechanical thrombectomies in acute bilateral middle cerebral artery strokes: A case report and review of literature.Journal of neurosciences in rural practiceArticle
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesPatients with acute ischemic stroke (AIS) treated with endovascular thrombectomy (EVT) in the late window (6-24 hours) can be evaluated with CT perfusion (CTP) or with noncontrast CT (NCCT) only. Whether outcomes differ depending on the type of imaging selection is unknown. We conducted a systematic review and meta-analysis comparing outcomes between CTP and NCCT for EVT selection in the late therapeutic window.
methodsThis study is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses 2020 guidelines. A systematic literature review of the English language literature was conducted using Web of Science, Embase, Scopus, and PubMed databases. Studies focusing on late-window AIS undergoing EVT imaged through CTP and NCCT were included. Data were pooled using a random-effects model. The primary outcome of interest was rate of functional independence, defined as modified Rankin scale 0-2. The secondary outcomes of interest included rates of successful reperfusion, defined as thrombolysis in cerebral infarction 2b-3, mortality, and symptomatic intracranial hemorrhage (sICH).
resultsFive studies with 3,384 patients were included in our analysis. There were comparable rates of functional independence (odds ratio [OR] 1.03, 95% CI 0.87-1.22; DISCUSSION: Although recovery of functional independence after late-window EVT was not more common in patients selected by CTP when compared with patients selected by NCCT only, patients selected by CTP had lower mortality.
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