Evidence map›Paper›PMID 36990717›Full record

ArticleNeurology2023

Clinical Reasoning: An 82-Year-Old Woman With Subacute Ophthalmoparesis and Ataxia.

Marc Rodrigo-Gisbert, Arnau Llaurado, Andres Baucells, Cristina Auger, Victoria González

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. The RiDDLE- expanding the spectrum of anti-Ri paraneoplastic neurological syndrome: diagnostic and therapeutic challenges.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Marc Rodrigo-GisbertFrom the Department of Neurology (M.R.-G., A.L., V.G.), Department of Immunology (A.B.), and Department of Neuroradiology (C.A.), University Hospital Vall d'Hebron, Barcelona.ORCID 0000-0002-7953-3795
Arnau LlauradoFrom the Department of Neurology (M.R.-G., A.L., V.G.), Department of Immunology (A.B.), and Department of Neuroradiology (C.A.), University Hospital Vall d'Hebron, Barcelona.ORCID 0000-0002-4655-6157
Andres BaucellsFrom the Department of Neurology (M.R.-G., A.L., V.G.), Department of Immunology (A.B.), and Department of Neuroradiology (C.A.), University Hospital Vall d'Hebron, Barcelona.ORCID 0000-0002-4567-8486
Cristina AugerFrom the Department of Neurology (M.R.-G., A.L., V.G.), Department of Immunology (A.B.), and Department of Neuroradiology (C.A.), University Hospital Vall d'Hebron, Barcelona.ORCID 0000-0001-9846-4767
Victoria GonzálezFrom the Department of Neurology (M.R.-G., A.L., V.G.), Department of Immunology (A.B.), and Department of Neuroradiology (C.A.), University Hospital Vall d'Hebron, Barcelona. m.gonzalez.7@vhebron.net.ORCID 0000-0002-0983-2052
Hebron University · PS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of an 82-year-old woman with subacute altered mental status, oculomotor disturbances, and ataxia. On examination, she exhibited bilateral ptosis, complete horizontal ophthalmoplegia, and limited vertical eye movements during upgaze associated with prominent truncal ataxia. Cerebral MRI showed a mild hyperintensity on T2 and fluid-attenuated inversion recovery sequences in the posterior brainstem extending to the upper cervical cord, without gadolinium enhancement. Clinical and radiologic features suggested an encephalomyelitis with prominent brainstem involvement. We summarize the comprehensive differential diagnosis in patients with subacute brainstem encephalitis, which includes infectious paraneoplastic syndromes and inflammatory disorders. This case highlights the relevance of performing a wide methodical screening for malignancy in case of negative initial workup.

Indexed as

Cerebellar AtaxiaOphthalmoplegiaAged, 80 and overAtaxiaClinical ReasoningContrast MediaFemaleGadoliniumHumansContrast MediaGadolinium

Identifiers

PMID36990717
PMCPMC10401681
OpenAlexW4361302528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.