Evidence map›Paper›PMID 36990648›Full record

ArticleBMJ open quality2023

Types of diagnostic errors reported by paediatric emergency providers in a global paediatric emergency care research network.

Prashant Mahajan, Joseph A Grubenhoff, Jim Cranford, Maala Bhatt, James M Chamberlain, Todd Chang, Mark Lyttle, Rianne Oostenbrink, Damian Roland, Richard M Rudy and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open quality, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Epidemiology of diagnostic errors in pediatric emergency departments using electronic triggers.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025
    Article
  2. Emergency Medicine: The Paradigm Shift.Journal of acute medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 13 institutions in 5 countries.

Prashant MahajanEmergency Medicine and Paediatrics, University of Michigan, Ann Arbor, Michigan, USA pmahajan@med.umich.edu.ORCID 0000-0003-4278-3560
Joseph A GrubenhoffPaediatric Emergency Medicine, University of Colorado Denver School of Medicine, Aurora, Colorado, USA.
Jim CranfordEmergency Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Maala BhattPaediatrics, University of Ottawa, Ottawa, Ontario, Canada.
James M ChamberlainEmergency Medicine, Children's National Medical Center, Washington, District of Columbia, USA.
Todd ChangPaediatric Emergency Medicine, Children's Hospital of Los Angeles, Los Angeles, California, USA.
Mark LyttlePaediatric Emergency Medicine, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Rianne OostenbrinkPaediatric Emergency Medicine, Erasmus MC-Sophia Children's Hospital, Rotterdam, UK.
Damian RolandPaediatric Emergency Medicine, University of Leicester, Leicester, UK.
Richard M RudyPaediatric Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Kathy N ShawPaediatric Emergency Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Robert Velasco ZunigaPaediatric Emergency Medicine, Hospital Universitario Rio Hortega, Valladolid, Spain.
Apoorva BelleEmergency Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Nathan KuppermannEmergency Medicine and Paediatrics, University of California Davis, Davis, California, USA.
Hardeep SinghMedicine - Health Services Research, Baylor College of Medicine, Houston, Texas, USA.
University of Michigan · USBaylor College of Medicine · USCalifornia University of Pennsylvania · USChildren's Hospital of Los Angeles · USChildren's National · USCincinnati Children's Hospital Medical Center · USErasmus MC - Sophia Children’s Hospital · NLHospital Universitario Río Hortega · ESUniversity Hospitals Bristol NHS Foundation Trust · GBUniversity of California, Davis · USUniversity of Colorado Denver · USUniversity of Leicester · GBUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiagnostic errors, reframed as missed opportunities for improving diagnosis (MOIDs), are poorly understood in the paediatric emergency department (ED) setting. We investigated the clinical experience, harm and contributing factors related to MOIDs reported by physicians working in paediatric EDs.

methodsWe developed a web-based survey in which physicians participating in the international Paediatric Emergency Research Network representing five out of six WHO regions, described examples of MOIDs involving their own or a colleague's patients. Respondents provided case summaries and answered questions regarding harm and factors contributing to the event.

resultsOf 1594 physicians surveyed, 412 (25.8%) responded (mean age=43 years (SD=9.2), 42.0% female, mean years in practice=12 (SD=9.0)). Patient presentations involving MOIDs had common undifferentiated symptoms at initial presentation, including abdominal pain (21.1%), fever (17.2%) and vomiting (16.5%). Patients were discharged from the ED with commonly reported diagnoses, including acute gastroenteritis (16.7%), viral syndrome (10.2%) and constipation (7.0%). Most reported MOIDs (65%) were detected on ED return visits (46% within 24 hours and 76% within 72 hours). The most common reported MOID was appendicitis (11.4%), followed by brain tumour (4.4%), meningitis (4.4%) and non-accidental trauma (4.1%). More than half (59.1%) of the reported MOIDs involved the patient/parent-provider encounter (eg, misinterpreted/ignored history or an incomplete/inadequate physical examination). Types of MOIDs and contributing factors did not differ significantly between countries. More than half of patients had either moderate (48.7%) or major (10%) harm due to the MOID.

conclusionsAn international cohort of paediatric ED physicians reported several MOIDs, often in children who presented to the ED with common undifferentiated symptoms. Many of these were related to patient/parent-provider interaction factors such as suboptimal history and physical examination. Physicians' personal experiences offer an underexplored source for investigating and mitigating diagnostic errors in the paediatric ED.

Indexed as

Emergency Service, HospitalPatient DischargeAdultChildDiagnostic ErrorsFemaleHumansMaleMissed DiagnosisPhysical Examinationdiagnostic errorsemergency departmentpaediatrics

Identifiers

PMID36990648
PMCPMC10069565
OpenAlexW4361199889

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.